Serum leptin concentration in pigs selected for high or low daily food intake

Cameron, N. D.; Penman, J.C.; McCullough, E.

doi:10.1017/s0016672399004383

Cited by 27 publications

(9 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Moreover, a decrease in insulin concentrations related to the decrease in feed intake is reported at high temperature in piglets [30], which also could account for the lack of effect of the meal on leptin concentrations. Finally, Cameron et al [2] indicate that leptin concentrations are more correlated to the pig adiposity than to its feed intake. As a consequence, the tendency of postprandial leptin concentrations to be decreased at high temperatures could be associated with the decrease in adipose tissue mass in our heatacclimated piglets.…”

Section: Resultsmentioning

confidence: 99%

Effects of high temperature on body temperature and hormonal adjustments in piglets

2002

View full text Add to dashboard Cite

-Effects of a high (33°C) or thermoneutral (23 °C) temperature on body temperature and endocrine parameters were studied in weaned piglets. Rectal and skin temperatures were measured in four ad libitum fed animals per temperature during three weeks. After this acclimation period, 11 blood samples were withdrawn on a 24-h period. Over the acclimation period, rectal and skin temperatures were 0.6 and 2.9°C higher, respectively, at 33°C than at 23°C (P < 0.01), this change occurring from the 1st day at 23 or 33°C. A tendency of serum leptin concentrations to be lower after meals at 33°C than at 23°C was also displayed (P = 0.09). Plasmatic concentrations in Insulin-like growth factor I and thyroxine were decreased at 33°C relative to 23°C (P < 0.01 and P < 0.06, respectively), and triiodothyronine concentrations tended to be lower at 33°C than at 23°C (P = 0.1), which could account for the lower heat production and growth observed in pigs exposed to high temperatures.piglet / heat exposure / body temperature / thyroid hormones / IGF-I Résumé -Effets d'une température ambiante élevée sur la température corporelle et les ajustements hormonaux chez le porcelet sevré. Les effets d'une température ambiante élevée (33°C) ou thermoneutre (23°C) sur la température corporelle et le statut hormonal sont étudiés chez le porcelet sevré. Les températures rectale et cutanée sont mesurées sur 4 animaux par tempé-rature, nourris à volonté et acclimatés à la température expérimentale pendant trois semaines. Après cette période, les paramètres sanguins sont mesurés sur 11 échantillons prélevés sur un nycthémère. Au cours de la période d'acclimatation, les températures rectale et cutanée sont rapidement supérieures à 33°C qu'à 23°C, respectivement de 0,6 et 2,9°C (P < 0,01). Les concentrations sériques en leptine tendent à être inférieures à 33°C à l'état nourri (P = 0,09). Les taux d'Insulin-like growth factor I et thyroxine plasmatiques sont plus faibles à 33 qu'à 23°C (respectivement P < 0,01 et P < 0,06), et les concentrations en triiodothyronine tendent à être inférieures à 33°C (P = 0,1), en accord avec la production de chaleur et la croissance plus faible de ces animaux au chaud.porcelet / chaleur / température corporelle / hormones thyroïdiennes / IGF-I Reprod. Nutr. Dev. 42 (2002) 45-53 45

show abstract

Section: Resultsmentioning

confidence: 99%

Effects of high temperature on body temperature and hormonal adjustments in piglets

2002

View full text Add to dashboard Cite

show abstract

“…Serum leptin level is more highly correlated with fat deposition (Cameron et al 2000), and serves as a signal reflecting the body fat content (Gill et al, 1997). In the current study, Jinhua gilts had higher leptin levels compared with Landrace gilts, which was in good agreement with carcass fat percentage.…”

Section: Discussionmentioning

confidence: 99%

“…In growing pigs, insulin increases glucose incorporation into fatty acids in adipose tissue in vivo (Dunshea et al 1992). And numerous studies indicate that serum letpin concentration is more highly correlated with fat deposition (Cameron et al 2000) and serves as a signal reflecting the body fat content (Gill et al 1997). The Jinhua pig is one of the most important Chinese local varieties characterized by low growth rate and high adiposity (Xu 1994).…”

mentioning

confidence: 99%

Developmental patterns in hormone and lipid metabolism of growing Jinhua and Landrace gilts

Miao¹,

Wang²,

Xu³

et al. 2008

Can. J. Anim. Sci.

View full text Add to dashboard Cite

. 2008. Developmental patterns in hormone and lipid metabolism of growing Jinhua and Landrace gilts. Can. J. Anim. Sci. 88: 601Á607. The aim of the present study was to investigate the developmental patterns of lipid metabolism, hormones and growth factor in Jinhua and Landrace gilts. Six purebred gilts of each breed were selected and slaughtered for analyses at 35, 80, and 125 d of age, respectively. Jinhua gilts contained less lean meat (PB0.01), and more carcass fat (PB0.05) compared with Landrace gilts. Serum leptin, insulin-like growth factor I (IGF-I) and insulin levels increased with age, whereas, free triiodothyronine (FT 3 ) and free thyroxine (FT 4 ) levels decreased with age in both breeds (PB0.05). Jinhua gilts had lower (PB0.05) serum IGF-I, FT 3 and FT 4 levels, and higher (PB0.05) serum leptin and insulin levels compared with Landrace gilts. Fatty acid synthase (FAS) activity of Jinhua gilts was higher than that of Landrace gilts (PB0.001), whereas Jinhua gilts had lower hormone-sensitive lipase (HSL) activity (PB0.001). Jinhua gilts had lower (PB0.05) levels of free fatty acid (FFA) and triacylglycerol (TG). These results suggest that hormone and growth factors could induce changes in lipid metabolism that inhibit fat synthesis through reducing lipogenic enzymes activities and promote fat degradation by increasing HSL activity, and therefore induce differences in carcass characteristics in the two breeds.

show abstract

“…Serum letpin level is more highly correlated with fat deposition (Cameron et al, 2000), and serves as a signal refl ecting the body fat content (Gill et al, 1997). Several reports demonstrated age-related changes of serum leptin concentrations in humans and rodents (Fried et al, 1998).…”

Section: Discussionmentioning

confidence: 99%

“…The protein product of the Ob gene named leptin, is secreted mainly by white adipose tissue (Zhang et al, 1994). Numerous studies indicate that serum letpin concentration is highly correlated with fat deposition (Cameron et al, 2000), and serves as a signal refl ecting the body fat content (Gill et al, 1997). In addition, thyroid hormones affect synthesis, mobilization and degradation of lipids (Pucci et al, 2000), insulin is mainly to stimulate glycogen synthesis, fatty deposition and inhibit gluconeogenesis (Ehterton et al, 1982;Chung et al, 1983).…”

Section: Introductionmentioning

confidence: 99%

Age-related changes of serum leptin, insulin, IGF-I and thyroid hormones levels in growing Jinhua and Landrace gilts

Miao¹,

Wang²,

Zhang³

et al. 2008

J. Anim. Feed Sci.

View full text Add to dashboard Cite

The present study was aimed to investigate the age-related changes of the serum IGF-I, leptin, insulin, triiodothyronine (T 3 ) and thyroxine (T 4 ) levels in pigs of different breeds. Jinhua and Landrace gilts were sampled at 35, 80 and 125 days of age, respectively. Serum hormone levels were measured with RIA. Serum IGF-I, leptin levels increased with age and displayed breed differences. Jinhua gilts showed lower (P<0.05) serum IGF-I and higher (P<0.05) leptin levels compared with Landrace gilts. In contrast, serum T 3 , T 4 levels decreased with age, Jinhua gilts had lower serum T 4 levels at 80 days of age. Meanwhile, Jinhua gilts had higher (P<0.01) serum insulin levels. Serum leptin, IGF-I, insulin and T 4 levels correlated with carcass fat content (P<0.05), which suggested that the breed differences of serum hormone levels may contribute to the different phenotypes in adipose tissue deposition.

show abstract

Serum leptin concentration in pigs selected for high or low daily food intake

Cited by 27 publications

References 16 publications

Effects of high temperature on body temperature and hormonal adjustments in piglets

Effects of high temperature on body temperature and hormonal adjustments in piglets

Developmental patterns in hormone and lipid metabolism of growing Jinhua and Landrace gilts

Age-related changes of serum leptin, insulin, IGF-I and thyroid hormones levels in growing Jinhua and Landrace gilts

Contact Info

Product

Resources

About