Serum lipids, glucose and insulin levels in healthy schoolchildren aged 9 and 15 years from central Sweden: Reference values in relation to biological, social and lifestyle factors

Wennlöf, Anita Hurtig; Yngve, Agneta; Nilsson, Torbjörn; Sjöstróm, Michael

doi:10.1080/00365510410003110

Cited by 51 publications

(53 citation statements)

References 139 publications

(166 reference statements)

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“…The homeostasis model assessment (HOMA) was calculated [16] as fasting insulin (mU/l)×fasting glucose (mmol/l)/22.5 (to convert insulin values in mU/l to pmol/l multiply by 6.945). A detailed description of the blood analysis has been reported elsewhere [17].…”

Section: Methodsmentioning

confidence: 99%

Markers of insulin resistance are associated with fatness and fitness in school-aged children: the European Youth Heart Study

et al. 2007

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Aims/hypothesis Our aim was to examine the association between markers of insulin resistance and: (1) body fat and waist circumference, taking into account cardiorespiratory fitness in school-aged children; and (2) cardiorespiratory fitness at differing levels of body fat and waist circumference. Subjects and methods This was a cross-sectional study of 873 children aged 9.6±0.4 years from Estonia and Sweden. Weight, height and waist circumference were measured. Body fat was expressed as the sum of five skinfold thicknesses. Cardiorespiratory fitness was estimated by a maximal cycle-ergometer test. The studied markers of insulin resistance were fasting insulin and glucose, and homeostasis model assessment (HOMA). Results HOMA and fasting insulin were positively associated with body fat and waist circumference after adjusting for cardiorespiratory fitness, age, pubertal status and study location. HOMA and fasting insulin were negatively associated with cardiorespiratory fitness in children in the third (highest) tertile of body fat and waist circumference after controlling for sex, age, pubertal status and study location. Fasting glucose was negatively associated with cardiorespiratory fitness in children in the third (highest) tertile of waist circumference, but it was not associated when body fat was taken into account. Conclusions/interpretation In school-aged children, HOMA and fasting insulin are significantly associated with body fat and waist circumference. In addition, cardiorespiratory fitness explains a significant proportion of the HOMA and fasting insulin variance in those children with high levels of body fat and waist circumference. The findings suggest that the deleterious consequences ascribed to high fatness could be counteracted by having high levels of cardiorespiratory fitness.

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Section: Methodsmentioning

confidence: 99%

Markers of insulin resistance are associated with fatness and fitness in school-aged children: the European Youth Heart Study

et al. 2007

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“…n Includes 47 cross-sectional studies (Brage et al 2004a(Brage et al , 2004bGutin et al 2005b;Wennlof et al 2005;Andersen et al 2006;Ekelund et al 2006Ekelund et al , 2009Hurtig-Wennlof et al 2007;Quiros-Tejeira et al 2007;Rizzo et al 2007Rizzo et al , 2008Butte et al 2007b;Ruiz et al 2007;Leary et al 2008;Mark and Janssen 2008;Sardinha et al 2008;Sakuragi et al 2009;Schofield et al 2009;LeBlanc and Janssen 2010;Nguyen et al 2010;Owen et al 2010;Carson and Janssen 2011;Holman et al 2011;Moreira et al 2011;Colley et al 2012;Hay et al 2012;Hearst et al 2012;Henderson et al 2012;Jimenez-Pavon et al 2012, 2013b, 2013cMartinez-Gomez et al 2012;Mota et al 2012;Mendoza et al 2012;Barreira et al 2013;Carson et al 2013;Chaput et al 2013;Janssen et al 2013;Lamotte et al 2013;Knowles et al 2013;Loprinzi et al 2013;Rey-Lopez et al 2013;…”

Section: Mpamentioning

confidence: 99%

Systematic review of the relationships between objectively measured physical activity and health indicators in school-aged children and youth

Poitras

Gray

Borghese

et al. 2016

Appl. Physiol. Nutr. Metab.

1,553

1,229

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Moderate-to-vigorous physical activity (MVPA) is essential for disease prevention and health promotion. Emerging evidence suggests other intensities of physical activity (PA), including light-intensity activity (LPA), may also be important, but there has been no rigorous evaluation of the evidence. The purpose of this systematic review was to examine the relationships between objectively measured PA (total and all intensities) and health indicators in school-aged children and youth. Online databases were searched for peer-reviewed studies that met the a priori inclusion criteria: population (apparently healthy, aged 5-17 years), intervention/exposure/comparator (volumes, durations, frequencies, intensities, and patterns of objectively measured PA), and outcome (body composition, cardiometabolic biomarkers, physical fitness, behavioural conduct/pro-social behaviour, cognition/academic achievement, quality of life/well-being, harms, bone health, motor skill development, psychological distress, self-esteem). Heterogeneity among studies precluded meta-analyses; narrative synthesis was conducted. A total of 162 studies were included (204 171 participants from 31 countries). Overall, total PA was favourably associated with physical, psychological/social, and cognitive health indicators. Relationships were more consistent and robust for higher (e.g., MVPA) versus lower (e.g., LPA) intensity PA. All patterns of activity (sporadic, bouts, continuous) provided benefit. LPA was favourably associated with cardiometabolic biomarkers; data were scarce for other outcomes. These findings continue to support the importance of at least 60 min/day of MVPA for disease prevention and health promotion in children and youth, but also highlight the potential benefits of LPA and total PA. All intensities of PA should be considered in future work aimed at better elucidating the health benefits of PA in children and youth.Key words: physical activity, body composition, cardiometabolic biomarkers, fitness, behavioural conduct, bone health, academic achievement, quality of life, well-being, children.Résumé : L'activité physique d'intensité moyenne à vigoureuse (« MVPA ») est essentielle à la prévention des maladies et à la promotion de la santé. D'après de récentes données, l'activité physique (« PA ») pratiquée à d'autres intensités telles que légères (« LPA ») s'avère aussi importante, mais il n'y a pas d'évaluation rigoureuse de ces faits. Cette analyse documentaire systématique a pour objectif d'examiner la relation entre l'activité physique mesurée objectivement (totale et à chacune des intensités) et des indicateurs de la santé chez des enfants et des jeunes d'âge scolaire. On a cherché dans des bases de données en ligne pour identifier des études révisées par des pairs et présentant a priori les critères d'inclusion suivants : population (apparemment en santé, sujets âgés de 5 à 17 ans), intervention/exposition/comparateur (volume, durée, fréquence, intensité et types de mesure objective de PA) et le résultat (composition c...

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“…EYHS was a school-based cross-sectional study of youth with TD, where PA and sedentary time were measured using an Actigraph accelerometer (model 7164; ActiGraph LLC, Pensacola, FL) in the same way as used with the youth with disabilities in the present study. Study design, selection criteria, and basic characteristics of the participants in the EYHS are reported elsewhere (Hurtig-Wennlöf, Yngve, Nilsson & Sjöström, 2005;Wennlöf, Yngve, & Sjöström, 2003).…”

Section: Participantsmentioning

confidence: 99%

Accelerometer-Assessed Physical Activity and Sedentary Time in Youth With Disabilities

Lobenius-Palmér

Sjöqvist

Hurtig-Wennlöf

et al. 2018

Adapted Physical Activity Quarterly

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This study compared accelerometer-assessed habitual physical activity (PA), sedentary time, and meeting PA recommendations among 102 youth with disabilities (7-20 years) in four subgroups-physical/visual impairments, intellectual disability, autism spectrum disorders, and hearing impairment-and 800 youth with typical development (8-16 years). Low proportions of youth with disabilities met PA recommendations, and they generally were less physically active and more sedentary than youth with typical development. The hearing impairment and autism spectrum disorder groups were the most and least physically active, respectively. Older age and to some extent female sex were related to less PA and more sedentary time. Considering the suboptimal levels of PA in youth with disabilities, effective interventions directed at factors associated with PA among them are needed.

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Serum lipids, glucose and insulin levels in healthy schoolchildren aged 9 and 15 years from central Sweden: Reference values in relation to biological, social and lifestyle factors

Cited by 51 publications

References 139 publications

Markers of insulin resistance are associated with fatness and fitness in school-aged children: the European Youth Heart Study

Markers of insulin resistance are associated with fatness and fitness in school-aged children: the European Youth Heart Study

Systematic review of the relationships between objectively measured physical activity and health indicators in school-aged children and youth

Accelerometer-Assessed Physical Activity and Sedentary Time in Youth With Disabilities

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