Serum procalcitonin as a predicting value in severity and prognosis of CAP in sickle cell patients

Abstract

predicted risk for mortality. [1,2] Pneumonia severity index (PSI) is a well-validated scoring system that assesses the risk of death in a two-step algorithm and was developed to identify patient at low risk for mortality. [3] However, it is complex and strongly dependent on age, limiting its general implementation in routine care. The less complex CURB65 (confusion, urea >7 mmol•L −1 , respiratory frequency ≥30 breaths•min −1 , low blood pressure (systolic value <90 mmHg or diastolic value ≤60 mmHg) and age ≥65 yrs) score, focuses on five predictors. [4] This score is easier to calculate, but has a slightly inferior prognostic accuracy. Both risk scores were validated for the prediction of mortality only, and their ability to predict other CAPassociated adverse outcomes is not validated. Both scores have limitations for clinical use, including practicability, risk of miscalibration, and only moderate sensitivity and specificity, which leads to hospitalization of patients where outpatient treatment would have been preferable. [5] Thus, additional risk factors and prognostic biomarkers potentially

Predictive Value of Sepsis Markers in Diabetic Ketoacidosis Patients Admitted to Intensive Care Unit

“…Creatinine and urea nitrogen levels are simultaneously determined from tube samples. Within an hour, all report results were obtained (8) .…”