Serum selenium levels in healthy adults and its changes in chronic renal failure

Kostakopoulos, A.; Κότσαλος, Αθανάσιος; Alexopoulos, J.; Sofras, F.; Deliveliotis, Ch.; Kallistratos, G.

doi:10.1007/bf02549802

Cited by 20 publications

(12 citation statements)

References 8 publications

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“…Serum Se concentrations between 0.51 and 1.79 mmolaL have been reported for European populations (for example, Kostakopoulos et al, 1990;Ringstad et al, 1991). In the 1970s the serum Se concentrations in the Finnish population ranged from 0.63±0.76 mmolaL (Alfthan, 1988;Knekt et al, 1990) being among the lowest ones in Europe.…”

Section: Discussionmentioning

confidence: 96%

The serum selenium concentrations in children and young adults: a long-term study during the Finnish selenium fertilization programme

et al. 1998

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Objective: To investigate the effects of the Finnish nationwide selenium (Se) fertilization programme on the Se status of the population. Design and subjects: Serum Se concentrations from 1985±1992 from 1568 healthy children and young adults in southwestern Finland were determined using direct electrothermal atomic absorption spectrometry. Results: The mean concentration in young adults increased from 1.04 mmol/L in 1985 to 1.59 mmol/L in 1990. Children younger than 15 y had lower concentrations than adults, with an increase from 0.87 mmol/L in 1985 to 1.31 mmol/L in 1990. The younger the children, the lower the Se concentrations tended to be. At the age of about seven months no signi®cant difference was noted between breast-fed and formula-fed infants. From 1991, when the amount of Se added to fertilizers was reduced and less foreign high-Se cereal was imported, the Se concentrations decreased in all age groups. Conclusions: The nationwide Se supplementation programme has succeeded in elevating the Se intake and the serum Se concentrations in the Finnish population. Sponsorship: Supported by the Juho Vainio Foundation and the Sigrid Juselius Foundation, Finland.

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Section: Discussionmentioning

confidence: 96%

The serum selenium concentrations in children and young adults: a long-term study during the Finnish selenium fertilization programme

et al. 1998

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“…As far as we know, there are limited studies determining serum selenium in population-based Greek cohorts. Moreover, those studies have either focused on certain population groups [8,9] or have had a low number of participants [7,15,16]. In addition, inadequate data about different factors such as anthropometric parameters and dietary habits as well as biochemical confounders that may influence the selenium status have been presented.…”

Section: Discussionmentioning

confidence: 99%

Serum Total Selenium Status in Greek Adults and Its Relation to Age. The ATTICA Study Cohort

Letsiou

Nomikos

Panagiotakos

et al. 2008

Biol Trace Elem Res

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The trace element selenium is an essential micronutrient for human health and its low levels in serum are implicated in the pathogenesis of several chronic diseases. Therefore, the determination of total selenium in serum may contribute to the assessment of the health and nutritional status of certain populations. The objective of the present work was to determine total selenium in the serum of 506 healthy volunteers that participated in the ATTICA study. Selenium was determined in serum by using the technique of inductively coupled plasma mass spectrometry. The mean serum selenium concentration was determined to be 91.8 +/- 33.7 microg/L (N = 506); 87.6% of women and 88.5% of men had serum selenium concentration below 125 microg/L, the cutoff considered to be required for optimal glutathione peroxidase activity. No association was found between serum selenium levels and the gender of the participants while a significant decline of selenium with age (p < 0.0001) was observed. According to our results, no anthropometric, lifestyle, nutritional, or biochemical indices were able to affect the association between serum selenium and age. This result may indicate that other factors such as selenium distribution as well as retention may be affecting the relationship between serum selenium and age.

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“…Of those elements, selenium (Se) acts as a major antioxidant in the form of selenoproteins to mitigate the cytotoxic effects of reactive oxygen species [3][4]. A number of studies have been reported on selenium level [5][6][7][8][9], food source [10][11][12][13], racial differences [14], deficiency [15][16][17], and toxicity [18]. Se concentration in the biological fluids varies considerably inside the global population, and normal ranges for typical populations are different [19].…”

Section: Introductionmentioning

confidence: 99%

Serum Selenium Level in Healthy Koreans

Kim

Galindev

Sei

et al. 2009

Biol Trace Elem Res

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Of trace elements in the serum of living organisms, selenium (Se) is an essential mineral and plays the role of an antioxidant as selenoproteins protecting the organism against oxidative damage induced by hydrogen peroxide, other lipid hydroperoxides, and their derivatives. The aim of this study was to determine the mean serum Se levels in healthy Korean volunteers (50 males and 50 females) by using an inductively coupled plasma-mass spectrometry method. The samples were collected at the Health Promotion Centre of Kangnam St. Mary's Hospital, College of Medicine, the Catholic University of Korea, Kangnam District, Seoul in accordance with procedures approved by the Institutional Review Board of the Catholic University of Korea. The mean serum Se level in healthy subjects was 112.05 +/- 30.42 microg/l. For gender, it was 120.81 +/- 27.37 microg/l for females and 103.29 +/- 31.05 microg/l for males. From the study result, there was a significant difference between the mean Se concentrations of gender groups (p = 0.0035). Also, the study indicated no effect of age on Se levels (p > 0.05) in the healthy individuals.

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Serum selenium levels in healthy adults and its changes in chronic renal failure

Cited by 20 publications

References 8 publications

The serum selenium concentrations in children and young adults: a long-term study during the Finnish selenium fertilization programme

The serum selenium concentrations in children and young adults: a long-term study during the Finnish selenium fertilization programme

Serum Total Selenium Status in Greek Adults and Its Relation to Age. The ATTICA Study Cohort

Serum Selenium Level in Healthy Koreans

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