1970
DOI: 10.3329/taj.v20i1.3082
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Serum Thyroxine & Triiodothyronine Levels in Normal Pregnancy and Pre-Eclampsia

Abstract: To evaluate the thyroid hormone levels in pre-eclampsia and normal pregnancy, a study was undertaken among 54 women of age ranged from 18 to 35 years without present or past history of thyroid diseases. Among the study subjects, 32 women were patients of pre-eclampsia, 12 women were in their normal third trimester pregnancy and 10 women were married but nonpregnant (without having hormonal contraceptives at least for 6 months). We have measured serum levels of total and free thyroxine (TT 4 & FT 4 ) and total … Show more

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Cited by 8 publications
(8 citation statements)
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“…There were a significant (P<0.05) decrease from first to second trimester and there was a slight increase in their levels from second to third trimester this slight increase was significant (P<0.05) inT 4 and non-significant inT 3 levels. Our findings are in agreement with [50] who found that free thyroid hormones levels remain unchanged or decreased in pregnancy. The overall means value of T 3 and T 4 in pregnant camels at 1 st , 2 nd and 3 rd trimesters were (2.20 ± 0.15, 1.70 ± 0.08 and 1.90 ± 0.04ng/ml) and (15.24 ± 0.41, 13.20 ± 0.46 and14.3 ± 0.44 µg/ dl), respectively.…”
Section: Resultssupporting
confidence: 83%
“…There were a significant (P<0.05) decrease from first to second trimester and there was a slight increase in their levels from second to third trimester this slight increase was significant (P<0.05) inT 4 and non-significant inT 3 levels. Our findings are in agreement with [50] who found that free thyroid hormones levels remain unchanged or decreased in pregnancy. The overall means value of T 3 and T 4 in pregnant camels at 1 st , 2 nd and 3 rd trimesters were (2.20 ± 0.15, 1.70 ± 0.08 and 1.90 ± 0.04ng/ml) and (15.24 ± 0.41, 13.20 ± 0.46 and14.3 ± 0.44 µg/ dl), respectively.…”
Section: Resultssupporting
confidence: 83%
“…In our study we evaluated thyroid hormone levels in normal pregnancy and in preeclamptic women. Evaluation in serum thyroid hormone levels in pregnancy indicates an important modification of thyroid activity in pregnancy [8]. In our study serum TT4 and TT3 were significantly higher in pregnant women compared to non-pregnant subjects, whereas FT4 and FT3 were almost same in both groups.…”
Section: Discussionsupporting
confidence: 47%
“…In preeclampsia liver, kidney and brain are mostly affected. Due to autointoxication functional disorders in these organs are evident [8]. As liver kidney and muscles are the main organs of peripheral deiodination of T 4 to T 3 , the serum concentration of T 4 and T 3 may different in preeclampsia than in normal pregnancy [5].…”
Section: Introductionmentioning
confidence: 99%
“…The decrease in FT3 levels probably appears because of the loss of proteins and protein-bound hormones in the urine. There are conflicting results regarding the higher FT4 levels in preeclampsia [22,[25][26][27][28][29].…”
Section: Discussionmentioning
confidence: 98%