Sesame (
Sesamum indicum
) is one of the oldest crops in the world and is a valuable source of vegetable oil. It has one of the highest oil content (up to 60%) among oil crops and one of the most stable oils due to the presence of a number of antioxidants. A major part of the sesame production is found in developing countries with the largest areas in India, Myanmar, China, Sudan, Nigeria, and Uganda. In comparison with soybean, rapeseed, or sunflower, sesame is a minor oil crop in the world and one of the reasons is insufficient breeding. Crop development programs for sesame, either small or nonexistent, have only involved conventional breeding, and little progress has been made during the past years. Various diseases and insect pests cause considerable damage and reduce the yield. Indeterminate flowering and dehiscent capsules are also important factors limiting sesame production. A revitalization of sesame research using modern plant breeding technologies can greatly improve the crop. Over the past 10 years, genetic engineering has greatly influenced the development of most of the predominant crops in the world. A biotechnological approach could definitely play an important role in genetic amelioration of sesame.