Sesquiterpene Lactones and Pentamethoxylated Flavone from Artemisia kulbadica Boiss. &amp; Buhse

Rustaiyan, A.; Ezzatzadeh, Elham

doi:10.1055/s-0031-1282128

Cited by 9 publications

(10 citation statements)

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“…E-mail: evalizade@yahoo.com. kulbadica new sesquiterpene lactones and penta methoxylated flavones (Rustaiyan and Ezzatzadeh, 2011). In continuation of our studies on the chemical composition of the essential oils (Morteza-Semnani et al, 2002;Morteza-Semnani and Saeedi, 2003), we decided to investigate Artemisia fragrans Willd., a species which grows in Armenia, Iran, Russia and neighboring domains.…”

Section: Introductionmentioning

confidence: 96%

Evaluating antibacterial activity from essential oil of Artemisia fragrans Willd. in North-Western of Iran

Gul¹,

Masud²,

Maqsood³

et al. 2012

Afr. J. Microbiol. Res.

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The antibacterial effects of Artemisia fragrans essential oil were studied in this research. The composition of essential oil from aerial parts was analyzed by GC/MS and its antibacterial effects were determined by disk diffusion method. In this study the antibacterial effects of essential oil of A. fragrans on two types of Gram positive bacteria Staphylococcus aureus, Strep. Enterococcus fecalis and Gram negative bacteria; Escherichia coli, Salmonella typhi, Pseudomonas aeruginosa and Klebsiella pneumonia by disk diffusion method on Mueller Hinton agar medium, were evaluated. The oil in concentrations 0, 10, 25, 50, 75, 100 percent prepared in DMSO and then 50 mg ml -1 A. fragrans essential oil was each was added to the specified disks. The present study describes the phytochemical profile and antibacterial activity of essential oil of A. fragrans. The antibacterial test results showed that the oil had a potential antibacterial activity against Gram positive bacterial strains that were mentioned. Essential oil showed maximum zone of inhibition concentration against Escherichia coli and Klebsiella pneumonia and minimal inhibition concentration against other Gram-negative bacteria that were studied.

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Section: Introductionmentioning

confidence: 96%

Evaluating antibacterial activity from essential oil of Artemisia fragrans Willd. in North-Western of Iran

Gul¹,

Masud²,

Maqsood³

et al. 2012

Afr. J. Microbiol. Res.

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show abstract

“…Sesqui-terpene lactones were used for their therapeutic and other properties, 10 recently, monoterpenes, sesqui-terpenes, sesqui-terpene lactones, flavonoids, coumarins, sterols, poly-acetylenes have been isolated from Artemisia species. 11 Isolated compounds from Artemisia judaica have exhibited antiviral, antibacterial, antifungal, and cytoprotective effects, [12][13][14] and used for the treatment of hepatitis, cancer and menstrual-related disorders, 15 Artemisia judaica showed a promising cytotoxic activity against some cancer cell lines, 16 which may be due to its essential oil content of thujone. 17 The present study is designed to evaluate the antimicrobial and cytotoxic effect of methanolic extract of Artemisia judaica leaves and stem with mechanistic determination of its cytotoxic effect on different cell lines.…”

Section: Introductionmentioning

confidence: 99%

In-vitro Evaluation of Anti-microbial and Cytotoxic Activity of Artemisia judaica Leaves and Stem Extracts via Induction of Caspase Dependent Apoptosis

Younes¹,

Bin²,

Unissa³

et al. 2022

IJPER

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Medicinal plants and herbs are commonly used in the world to treat various human disorders. Artemisia judaica is one of these herbal species that is commonly used in medicine due to its contents of many bioactive compounds such as; flavonoids, lactones, essential oil and sesqui-terpenoids. It was used in many traditional medicines as an anthelmintic, antispasmodic, anti-rheumatic, and antibacterial agent. In recent years, anti-bacterial and anti-cancer activity of medicinal herbs are highly investigated. The present study is focused on the anti-microbial and cytotoxic effect of methanolic extract of Artemisia judaica leaves and stem. The antimicrobial assay was done on different gram-positive and gram-negative bacteria and it was revealed that leaves and stem extracts possess high and moderate activity against Staphylococcus aureus (MIC 312.5μg/ml and 625μg/ml) and Proteus vulgaris (MIC 312.5μg/ml and 1250μg/ml) for leaves and stem, respectively. Extracts were screened against HepG2, HCT-116, MCF-7, A-549 and MRC-5 cancer cells and it was found that both extracts were active against all cell lines with highest selectivity and cytotoxic activity observed against HepG2 cells (IC 50 = 3.38 and 6.84μg/ml, for leaves and stem respectively). Further mechanistic studies on HepG2 cells showed that both extracts resulted in S-phase arrest and induced apoptosis via activation of caspase-3, p53 and Bax

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“…Artemisinin is a sesquiterpene lactone derived from Siberi. Artemisinin has a chemical structure of endoperoxidiaxone that has biological activity, including antimalarial activity [11][12][13][14][15][16][17][18].…”

Section: Introductionmentioning

confidence: 99%

Investigation of Antioxidant Effects of Artemisia Sieberi Essential Oil In Iran

Kahrarian¹,

Mojarrab²,

Shahbazi³

2020

J Biotechnol Bioinforma Res

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Background: Nowadays, Due to the destructive effects of chemicals on processed foods and increasing multidrug-resistant pathogens (MDRs), the use of essential oils of medicinal plants, is essential. Artemisia is the largest genus of the Asteraceae family, with extensive research on the composition of essential oils, antimicrobial effects and food control of various species of this genus hasdone the purpose of this study was to review the antimicrobial effects of the four essential oils of Artemisia sieberi in Iran. Materials and Methods: This study data collectionby articles in internal databases such as, Irandoc, SID and external databases including Science Direct, Scopus, PubMed, Elsevier, Google Scholar, Directory of Open Access Be it. Results: Asteraceae family essential oils are biologically active secondary metabolites including volatile oils, quarines, flavonoids and phenolic carbonic acids that have potent antimicrobial effects. Chemical analysis of essential oils confirmed the four Artemisia species tested in Iran as effective antimicrobial agents. Therefore,the essential oils of these plants can be used as a food preservative and in the control of infectious diseases. Conclusion: Analysis of the essential oil composition of these plants depends on the geographical diversity of the region and different cultivation conditions. Iran is one of the richest regions of the world in terms of number and variety of these plants, identification, development and optimization of the extract of these plants can play an important role in the health of society, economy and production. This study may focus on the unknown potentials of Artemisia species in Iran.

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Sesquiterpene Lactones and Pentamethoxylated Flavone from Artemisia kulbadica Boiss. & Buhse

Cited by 9 publications

References 0 publications

Evaluating antibacterial activity from essential oil of Artemisia fragrans Willd. in North-Western of Iran

Evaluating antibacterial activity from essential oil of Artemisia fragrans Willd. in North-Western of Iran

In-vitro Evaluation of Anti-microbial and Cytotoxic Activity of Artemisia judaica Leaves and Stem Extracts via Induction of Caspase Dependent Apoptosis

Investigation of Antioxidant Effects of Artemisia Sieberi Essential Oil In Iran

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