Sesquiterpene Lactones of Leaves and Fruits of Laurus Nobilis L.

Коновалов, Д. А.; Насухова, Н. М.

doi:10.19163/2307-9266-2014-2-2(3)-23-33

Cited by 4 publications

(1 citation statement)

References 9 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Останнім часом особливу увагу приділяють сесквітерпеновим лактонам листя та плодів лавра благородного, що виявляють антибактеріальну, протигрибкову, протидіабетичну, протизапальну, гепатозахисну, нейрозахисну, цитотоксичну дію [21], та одержанню екстрактів за допомогою сучасних методів надкритичної флюїдної та СВЧ-екстракції [22]. У літературі є відомості щодо кількісного вмісту певних груп БАР в листі, пагонах лавра благородного, зокрема визначено вміст суми органічних кислот у пагонах -не менше 1,7 %, у листіне менше 1,9 %, вміст суми окиснюваних фенолів для обох видів сировини -не менше 4,5 %, суми кислот гідроксикоричних -не менше 1,3 %, суми флавоноїдів -не менше 0,8 %.…”

Section: ■ вступunclassified

Selection of the optimal extractant for the extraction of phenolic compounds from Laurus nobilis L. leaves

Posokhova¹,

Skrebtsova²,

Khvorost³

et al. 2021

J. Org. Pharm. Chem.

View full text Add to dashboard Cite

Aim. To select the optimal extractant for the extraction of a number of groups of phenolic compounds from Lаurus nоbilis L. leaves based on the determination of the quantitative content of these groups in the extracts obtained. Materials and methods. Lаurus nоbilis L. leaves were harvested in November 2020 from artificially cultivated specimens aged 5 – 7 years. The quantitative determination of polyphenols was performed using the spectrophotometric method at a wavelength of 760 nm in accordance with the requirements of the Supplement of the State Pharmacopoeia of Ukraine (SPhU) 1.2 (2.8.14). The quantitative content of this group of compounds was calculated with reference to pyrogalol and dried substance. The quantitative determination of the amount of hydroxycinnamic acids was performed according to the SPhU 2.2 monograph “Orthosyphon stamen (kidney tea) leavesN” by the spectrophotometric method at a wavelength of 505 nm and calculated with reference to rosmarinic acid. The quantitative determination of the amount of flavonoids was performed according to the SPhU 2.0 monograph “Hawthorn leaves and flowers” by the spectrophotometric method at a wavelength of 410 nm and calculated with reference to hyperoside.Results and discussion. The analysis of the results for the quantitative determination of polyphenols, the amount of hydroxycinnamic acids and the amount of flavonoids in extracts from Lаurus nоbilis L. leaves obtained using water, water-ethanol mixtures and 96 % ethanol showed that 70 % ethanol was optimal for extracting compounds of these groups. The quantitative content of polyphenols (calculated with reference to pyrogalol) was not less than 21 %, the amount of hydroxycinnamic acids (calculated with reference to rosmarinic acid) – not less than 3 %, the amount of flavonoids (calculated with reference to hyperoside) – not less than 5 %. Conclusions. For the first time, the quantitative content of a number of groups of phenolic compounds (polyphenols, the total amount of hydroxycinnamic acids, and the total amount of flavonoids) in Lаurus nоbilis L. leaves extracts obtained using various extractants has been determined. On this basis, the optimal extractant – 70 % ethanol for the extraction of phenolic compounds has been selected. The results obtained will be used when developing the technology for obtaining substances from Lаurus nоbilis L. leaves.

show abstract

Section: ■ вступunclassified

Selection of the optimal extractant for the extraction of phenolic compounds from Laurus nobilis L. leaves

Posokhova¹,

Skrebtsova²,

Khvorost³

et al. 2021

J. Org. Pharm. Chem.

View full text Add to dashboard Cite

show abstract

Comparison of Laurus Nobilis Extracts Composition Obtained by Microwave Extraction, Supercritical Fluid Extraction and Steam Distillation

Pokrovskiy¹,

Прокопчук²,

Bagatelia³

et al. 2019

JCPRM

View full text Add to dashboard Cite

A comparison of chemical composition of bay laurel extracts obtained by microwave extraction, supercritical fluid extraction and steam distillation was performed. Microwave extraction and steam distillation were shown to give similar essential oils. Microwave extract contains more monoterpenoid components, especially hydrocarbons. Steam distillation oil contains more sesquiterpenoid compounds, mostly oxygenated. SFE extract composition differs substantially from the ones obtained by two other methods. According to GC-MS data they contain much more sesquiterpenoid components, namely sesquiterpene lactones. This makes SFE a perspective candidate for isolation of biologically active compounds from laurel leaves. However, apart from valuable compound SFE extracts also contain substantial amounts of waxes as well as large quantities of some non-volatile component undetectable via GC-MS. In order to implement SFE into the practice of laurel processing one has to develop an approach for the fractionation of SFE extracts allowing isolating sesquiterpene lactone enriched fraction.

show abstract

Phenolic compounds of laurus nobilis (review)

Коновалов

Alieva

2019

Farm. farmakol. (Pâtigorsk)

Self Cite

View full text Add to dashboard Cite

Пятигорский медико-фармацевтический институт-филиал федерального государственного бюджетного образовательного учреждения высшего образования «Волгоградский государственный медицинский университет» Министерства здравоохранения Российской Федерации 357532, Россия, Ставропольский край, г. Пятигорск, пр. Калинина, 11 2 Федеральное государственное бюджетное образовательное учреждение высшего образования «Дагестанский государственный медицинский университет» Министерства здравоохранения Российской Федерации 367000, Россия, Республика Дагестан, г. Махачкала, пл. Ленина, 1.

show abstract

Sesquiterpene Lactones of Leaves and Fruits of Laurus Nobilis L.

Cited by 4 publications

References 9 publications

Selection of the optimal extractant for the extraction of phenolic compounds from Laurus nobilis L. leaves

Selection of the optimal extractant for the extraction of phenolic compounds from Laurus nobilis L. leaves

Comparison of Laurus Nobilis Extracts Composition Obtained by Microwave Extraction, Supercritical Fluid Extraction and Steam Distillation

Phenolic compounds of laurus nobilis (review)

Contact Info

Product

Resources

About