Sesquiterpenes from Essential Oil from Fruits of<i>Guarea macrophylla</i>Vahl ssp.<i>tuberculata</i>(Meliaceae)

Lago, João Henrique G.; Cornélio, Melânia Lopes; Moreno, Paulo Roberto Hrihorowitsch; Apel, Miriam Anders; Limberger, Renata Pereira; Henriques, Amélia T.; Roque, Nı́dia Franca

doi:10.1080/10412905.2005.9698838

Cited by 6 publications

(2 citation statements)

References 9 publications

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“…Despite the fact that the genus Guarea includes more than 50 species, few studies on the essential oils of its species have been published, namely, the Brazilian species G. guidonia [13,14,15], G. macrophylla ssp tuberculata [16,17,18] and the African species G. cedrata [19], whose dominant compounds differ from those found in the present study.…”

Section: Resultscontrasting

confidence: 58%

Chemical Composition and Larvicidal Activity against Aedes aegypti Larvae of Essential Oils from Four Guarea Species

et al. 2010

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The essential oils of four Guarea species collected at Manaus (Amazonas, Brazil) were obtained by hydrodistillation and analyzed by GC-MS. Except for one diterpene detected, the compounds identified in the essential oils were hydrocarbons and oxygenated sesquiterpenes. The major sesquiterpenes were α-santalene (26.26%) and α-copaene (14.61%) from G. convergens branches; caryophyllene epoxide (40.91%) and humulene epoxide II (14.43%) from G. humaitensis branches; cis-caryophyllene (33.37%) and α-trans-bergamotene (11.88%) from G. scabra leaves; caryophyllene epoxide (36.54%) in leaves and spathulenol (14.34%) in branches from G. silvatica. The diterpene kaurene (15.61%) was found in G. silvatica leaves. Larvicidal activity assay of essential oils against third-instar Aedes aegypti larvae revealed that at higher concentrations (500 and 250 μg/mL), all the essential oils caused 100% mortality after 24 h of exposure. The most active essential oils were those of G. humaitensis branches (LC50 48.6 μg/mL), G. scabra leaves (LC50 98.6 μg/mL) and G. silvatica (LC50 117.9 μg/mL). The differences in the toxicity of essential oils of Guarea species on A. aegypti are due to qualitative and quantitative variations of the components, therefore the larvicidal effect may be due to higher amount of the sesquiterpenes with caryophyllane skeleton.

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Section: Resultscontrasting

confidence: 58%

Chemical Composition and Larvicidal Activity against Aedes aegypti Larvae of Essential Oils from Four Guarea Species

et al. 2010

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“…The sample was analyzed by GC/MS in the same chromatographic conditions as described above, using a Shimadzu QP-5000-quadrupole MS system, operating with ionization energy of 70 eV and an interface temperature of 250°C, The identification of the oil components was accomplished by comparison of their GC retention indices as well as their mass spectra with corresponding data of authentic compounds or of components of reference oils; some mass spectra were compared with those of the NIST (National Institute of Standards and Technology) computer data library or with spectral data given in the literature (2)(3)(4). Analysis of oil by GC and GC/MS resulted in complete identification of 27 components of the total 31 detected comprising 98.8% of total volatiles.…”

Section: Present Workmentioning

confidence: 99%