Severe Acute Respiratory Syndrome

Hui, David Shu-Cheong; Zumla, Alimuddin

doi:10.1016/j.idc.2019.07.001

Cited by 449 publications

(223 citation statements)

References 94 publications

(174 reference statements)

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“…This disease proved to be highly infectious with respiratory droplets as the main route of transmission. Infected feces also played an important role in some cluster outbreak cases [17,18]. Fortunately, it has been proved that SARS patients are not infectious during the period of incubation (within 16 days of infection, usually 3-5 days).…”

Section: Sars-covmentioning

confidence: 99%

Coronavirus Disease 2019: Coronaviruses and Blood Safety

Chang

Yan

Wang

2020

Transfusion Medicine Reviews

597

602

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Section: Sars-covmentioning

confidence: 99%

Coronavirus Disease 2019: Coronaviruses and Blood Safety

Chang

Yan

Wang

2020

Transfusion Medicine Reviews

597

602

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“…Currently, the available COVID-19 genome sequences from clinical samples suggest that this viral emergence is related to bat coronaviruses [3]. Although the coronavirus infection in humans frequently presents with mild severity, the betacoronavirus infection of either the severe acute respiratory syndrome coronavirus (SARS-CoV) [4] or the Middle East respiratory syndrome coronavirus (MERS-CoV) [5] resulted in higher mortality rates [6]. Given the novelty of COVID-19, some characteristics of the virus remain yet unknown.…”

Section: Current Point Of Viewmentioning

confidence: 99%

Coronavirus COVID-19 impacts to dentistry and potential salivary diagnosis

2020

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“…The propensity of SARS-CoV and MERS-CoV to generate large hospital outbreaks has been well established [27,28]. The SARS epidemic in 2002-2003 emphasized that correct management of symptomatic cases within and outside hospital was crucial for containing the epidemic.…”

Section: Learning From the Sars And Mers Outbreaksmentioning

confidence: 99%

“…In fact, the correct management of several imported cases of SARS into Vancouver (British Columbia, Canada), resulted in stopping secondary transmissions within the city. In contrast, inadequate application of infection control measures in Toronto (Ontario, Canada) and Taipei (Taiwan) led to significant hospital clusters and further spread [28]. The case of MERS is even more emblematic and enigmatic.…”

Section: Learning From the Sars And Mers Outbreaksmentioning

confidence: 99%

Coronavirus infections: Epidemiological, clinical and immunological features and hypotheses

Raoult¹,

Zumla²,

Locatelli³

et al. 2020

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Coronaviruses (CoVs) are a large family of enveloped, positivestrand RNA viruses. Four human CoVs (HCoVs), the non-severe acute respiratory syndrome (SARS)-like HCoVs (namely HCoV 229E, NL63, OC43, and HKU1), are globally endemic and account for a substantial fraction of upper respiratory tract infections. Non-SARS-like CoV can occasionally produce severe diseases in frail subjects but do not cause any major (fatal) epidemics. In contrast, SARS like CoVs (namely SARS-CoV and Middle-East respiratory syndrome coronavirus, MERS-CoV) can cause intense short-lived fatal outbreaks. The current epidemic caused by the highly contagious SARS-CoV-2 and its rapid spread globally is of major concern. There is scanty knowledge on the actual pandemic potential of this new SARS-like virus. It might be speculated that SARS-CoV-2 epidemic is grossly underdiagnosed and that the infection is silently spreading across the globe with two consequences: (i) clusters of severe infections among frail subjects could haphazardly occur linked to unrecognized index cases; (ii) the current epidemic could naturally fall into a low-level endemic phase when a significant number of subjects will have developed immunity. Understanding the role of paucisymptomatic subjects and stratifying patients according to the risk of developing severe clinical presentations is pivotal for implementing reasonable measures to contain the infection and to reduce its mortality. Whilst the future evolution of this epidemic remains unpredictable, classic public health strategies must follow rational patterns. The emergence of yet another global epidemic underscores the permanent challenges that infectious diseases pose and underscores the need for global cooperation and preparedness, even during inter-epidemic periods.

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Severe Acute Respiratory Syndrome

Cited by 449 publications

References 94 publications

Coronavirus Disease 2019: Coronaviruses and Blood Safety

Coronavirus Disease 2019: Coronaviruses and Blood Safety

Coronavirus COVID-19 impacts to dentistry and potential salivary diagnosis

Coronavirus infections: Epidemiological, clinical and immunological features and hypotheses

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