Severe airway stenosis associated with Crohn's disease: Case report

Plataki, Maria; Tzortzaki, Eleni G.; Lambiri, Irini; Giannikaki, Elpida; Ernst, Armin; Siafakas, Nikolaos M.

doi:10.1186/1471-2466-6-7

Cited by 35 publications

(20 citation statements)

References 21 publications

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“…Since that report there have been small series but mostly isolated case reports. A spectrum of pulmonary involvement has been described, including: 1) airway disease (tracheal [4] and tracheobronchial [5] stenosis, tracheobronchitis [6], bronchitis [3], bronchiectasis [7], bronchiolitis [8] and asthma [9]); 2) interstitial lung disease (granulomatous alveolitis [10], bronchiolitis obliterans with organising pneumonia [11], interstitial fibrosis [12] and lung infiltrates with peripheral eosinophilia [13]); and 3) serositis (pleural thickening [12] and pleuropericarditis [13]). …”

Section: Discussionmentioning

confidence: 99%

Pulmonary necrobiotic nodules: a rare extraintestinal manifestation of Crohn's disease

Warwick¹,

Leecy²,

Silverstone³

et al. 2009

Eur Respir Rev

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The present article reports the case of a 22-yr-old female with new onset Crohn's colitis, anterior uveitis and multiple pulmonary nodules which, on histological examination, were necrobiotic nodules. This is a rare but recognised pulmonary extraintestinal manifestation of Crohn's disease and only the fourth reported case. The present case report is followed by a brief review of the relevant literature.

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Section: Discussionmentioning

confidence: 99%

Pulmonary necrobiotic nodules: a rare extraintestinal manifestation of Crohn's disease

Warwick¹,

Leecy²,

Silverstone³

et al. 2009

Eur Respir Rev

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“…Endoscopic studies revealed polypoid or pseudotumoural structures and/or circumferential inflammation obstructing the airway lumen. These lesions were friable and haemorrhagic [16,43,[47][48][49]. Histological examination showed granulation tissue and mixed inflammation with domination of lymphocytes and plasma cells [43,[47][48][49].…”

Section: Airways Diseases -Larynx Trachea Bronchi Bronchiolimentioning

confidence: 99%

“…It may occur at any level from the larynx to the segmental bronchi [16,43,[47][48][49]. Clinical presentation in these cases included dyspnoea, fever, expectoration, stridor and/or wheeze [16,43,[47][48][49].…”

Section: Airways Diseases -Larynx Trachea Bronchi Bronchiolimentioning

confidence: 99%

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Respiratory System Involvement in Inflammatory Bowel Diseases

Kacprzak¹,

Szturmowicz²,

Kuś³

2017

Advances in Respiratory Medicine

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“…Empirical data suggest initial treatment with systemically administered high doses of corticosteroids (prednisone 1 mg/kg of lean body weight administered orally or methylprednisolone 60-80 mg intravenously per day); these suggestions are drawn from case reports, however, and not from randomized controlled trials, and should therefore be critically viewed [3] . In refractory cases, rigid bronchoscopy and interventional bronchoscopy procedures (laser beam, balloon dilation, stent placement) may be required in order to maintain an adequate airway [49,50] .…”

Section: Upper Airwaysmentioning

confidence: 99%

Patterns of airway involvement in inflammatory bowel diseases

Papanikolaou

Kagouridis

Papiris

2014

WJGP

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Extraintestinal manifestations occur commonly in inflammatory bowel diseases (IBD). Pulmonary manifestations (PM) of IBD may be divided in airway disorders, interstitial lung disorders, serositis, pulmonary vasculitis, necrobiotic nodules, drug-induced lung disease, thromboembolic lung disease and enteropulmonary fistulas. Pulmonary involvement may often be asymptomatic and detected solely on the basis of abnormal screening tests. The common embryonic origin of the intestine and the lungs from the primitive foregut, the co-existence of mucosa associated lymphoid tissue in both organs, autoimmunity, smoking and bacterial translocation from the colon to the lungs may all be involved in the pathogenesis of PM in IBD. PM are mainly detected by pulmonary function tests and highresolution computed tomography. This review will focus on the involvement of the airways in the context of IBD, especially stenoses of the large airways, tracheobronchitis, bronchiectasis, bronchitis, mucoid impaction, bronchial granulomas, bronchiolitis, bronchiolitis obliterans syndrome and the co-existence of IBD with asthma, chronic obstructive pulmonary disease, sarcoidosis and a1-antitrypsin deficiency.© 2014 Baishideng Publishing Group Inc. All rights reserved. Key words: Inflammatory bowel diseases; Airways; BronchiolitisCore tip: The lung is commonly involved in inflammatory bowel diseases; however, airway involvement is often overlooked. This review will help gastroenterologists recognize the involvement of the airways in the context of inflammatory bowel diseases (IBD), especially stenoses of the large airways, tracheobronchitis, bronchiectasis, bronchitis, mucoid impaction, bronchial granulomas, bronchiolitis, bronchiolitis obliterans syndrome and the co-existence of IBD with asthma, chronic obstructive pulmonary disease, sarcoidosis and a1-antitrypsin deficiency, and appropriately manage their patients.Papanikolaou I, Kagouridis K, Papiris SA. Patterns of airway involvement in inflammatory bowel diseases. World J Gastrointest Pathophysiol

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Severe airway stenosis associated with Crohn's disease: Case report

Abstract: Background: Symptomatic respiratory tract involvement is not common in Crohn's disease. Upper-airway obstruction has been reported before in Crohn's disease and usually responds well to steroid treatment.

Cited by 35 publications

References 21 publications

Pulmonary necrobiotic nodules: a rare extraintestinal manifestation of Crohn's disease

Pulmonary necrobiotic nodules: a rare extraintestinal manifestation of Crohn's disease

Respiratory System Involvement in Inflammatory Bowel Diseases

Patterns of airway involvement in inflammatory bowel diseases

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