Severe allergic dermatitis caused by lanolin alcohol as part of an ointment base in propolis cream

Fellinger, Christina; Hemmer, Wolfgang; Wantke, F.; Wöhrl, Stefan; Jarisch, Reinhart

doi:10.1111/j.1600-0536.2012.02161.x

Cited by 5 publications

(1 citation statement)

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“…An ideal ointment base should possess the following properties such as should be pharmaceutically well-designed, should have a low manifestation of irritation, should be companionable with other ingredients, easily washable with water, secure on storage, have a low sensitization catalog and should release the medicament efficiently at the site of application (Fellinger et al, 2013). The USP recognizes four general classes of ointment bases to be used therapeutically or as vehicles for active ingredients.…”

Section: Ointment Basementioning

confidence: 99%

Comprehensive review on additives of topical dosage forms for drug delivery

2014

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Skin is the largest organ of the human body and plays the most important role in protecting against pathogen and foreign matter. Three important modes such as topical, regional and transdermal are widely used for delivery of various dosage forms. Among these modes, the topical dosage forms are preferred because it provides local therapeutic activity when applied to the skin or mucous membranes. Additives or pharmaceutical excipients (non-drug component of dosage form) are used as inactive ingredients in dosage form or tools for structuring dosage forms. The main use of topical dosage form additives are controling the extent of absorption, maintaining the viscosity, improving the stability as well as organoleptic property and increasing the bulk of the formulation. The overall goal of this article is to provide the clinician with information related to the topical dosage form additives and their current major applications against various diseases.

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Section: Ointment Basementioning

confidence: 99%