Severe Diarrhœa Associated With Lithium-Carbonate Therapy in Regional Ileitis

Regenerating Reputations: Are Wnt and Myc the Good Guys After All?

“…For this patient, lithium therapy was associated with improvement in both diseases [11]. On the other hand, in the same year another case report suggested lithium treatment as the cause of an acute ileitis in a patient [12], though the response was acute and likely not due to IBD per se. Surprisingly, there are no published metaanalyses examining the incidence of Crohn's disease or ulcerative colitis in patients taking lithium versus the general population.…”

Intestinal vasculitis and lithium carbonate-associated diarrhoea

“…There has been one previous report of severe diarrhoea associated with therapeutic serum lithium levels (Varsamis and Wand, 1972). In that case the patient, a previously well male, also developed an acute abdomen and an ileal resection was performed.…”

Lithium Carbonate Intoxication

“…The net result is decreased glu¬ cose and water absorption, leading to the above symptoms.There is little evidence that lithium carbonate exacerbates gastrointestinal tract disease. However, a flareup of re¬ gional enteritis has been associated with lithium carbonate therapy 116. …”