Severe Hyperkalemia in a Hematology–Oncology Patient

Leucocytosis‐induced plasma hyperkalaemia in samples conveyed by a pneumatic transport system: tips and tricks

“…In previous articles, including the recent case report published by Racek et al (), spurious hyperkalaemia has been documented in uncentrifuged plasma samples conveyed to laboratory by means of a pneumatic transport system (PTS). We also recently described the case of a child with high leucocytosis (i.e., 800 × 10 9 /l), whose uncentrifuged plasma samples were transported to the laboratory by PTS and then revealed a spurious increase of plasma potassium and an unexpected artefactual decrease of sodium in plasma (Grzych et al , ).…”

“…We also recently described the case of a child with high leucocytosis (i.e., 800 × 10 9 /l), whose uncentrifuged plasma samples were transported to the laboratory by PTS and then revealed a spurious increase of plasma potassium and an unexpected artefactual decrease of sodium in plasma (Grzych et al , ). Given that these electrolyte abnormalities are most likely to be attributable to the use of PTS, it was suggested that PTS should be avoided for convening blood samples with leucocytosis (Racek et al , ). Nevertheless, avoidance of sample transportation with PTS did not apparently solved the problem in our previously published case (Grzych et al , ).…”

Síndrome de lisis tumoral espontáneo en seminoma no gonadal retroperitoneal: reporte de caso

“…Cuando la capacidad de transporte luminal se ve sobrepasada y llega una gran carga de AU al túbulo distal y colector, este puede cristalizarse y precipitarse, generando obstrucción de los túbulos renales y, por ende, la LRA [22][23][24] . La hiperkalemia suele ser el primer desorden electrolítico evidenciado 25 , y sus manifestaciones clínicas varían desde síntomas gástricos, debilidad, calambres y parálisis hasta taquicardia o fibrilación ventricular, asistolia y muerte súbita 26 . La hiperfosfatemia es un hallazgo característico del SLT que sucede cuando la capacidad de excreción renal se encuentra sobrepasada, y puede manifestarse con náuseas, vómitos, diarrea y letargia, así como asociarse a hipocalcemia por su unión con este catión y generar cristalización 27 .…”