Severe Pneumonia Due to SARS-CoV-2 and Respiratory Syncytial Virus Infection: A Case Report

Shi, Bao; Xia, Zhi; Xiao, Shiyi; Huang, Chengjiao; Zhou, Xiaoqin; Xu, Hui

doi:10.1177/0009922820920016

Cited by 12 publications

(13 citation statements)

References 14 publications

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“…Testing for viral coinfection was reported in 30 infants, of whom 5 (17%) had positive testing; identified pathogens included RSV (n=2), rhinovirus/enterovirus (n=2), and seasonal coronavirus (n=1). ( 23 , 24 , 25 , 26 , 27 ) One neonate was diagnosed with human metapneumovirus coinfection after initial SARS-CoV-2 hospital admission; this neonate presented 5 days after initial discharge with poor feeding and respiratory distress and was readmitted. ( 18 )…”

Section: Resultsmentioning

confidence: 99%

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Community-Onset Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Young Infants: A Systematic Review

Mark

Golden

Gilmore

et al. 2021

The Journal of Pediatrics

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Section: Resultsmentioning

confidence: 99%

“…Two neonates were treated with intravenous immunoglobulin, one in the setting of suspected myocarditis and the other with RSV coinfection and severe pneumonia requiring CPAP. ( 17 , 25 )…”

Section: Resultsmentioning

confidence: 99%

Community-Onset Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Young Infants: A Systematic Review

Mark

Golden

Gilmore

et al. 2021

The Journal of Pediatrics

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“… 41 A severe case of COVID-19 has been reported in a Chinese 2-month-old infant who had coinfection with respiratory syncytial virus (RSV). 42 …”

Section: Risk Factors For Severity In Coronavirus Disease 2019 and Otmentioning

confidence: 99%

Risk Factors for Severity in Children with Coronavirus Disease 2019

Tsabouri

Makis

Kosmeri

et al. 2021

Pediatric Clinics of North America

115

100

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The coronavirus disease 2019 (COVID-19) pandemic has affected hundreds of thousands of people. The authors performed a comprehensive literature review to identify the underlying mechanisms and risk factors for severe COVID-19 in children. Children have accounted for 1.7% to 2% of the diagnosed cases of COVID-19. They often have milder disease than adults, and child deaths have been rare. The documented risk factors for severe disease in children are young age and underlying comorbidities. It is unclear whether male gender and certain laboratory and imaging findings are also risk factors. Reports on other potential factors have not been published.

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“…Cough: Initial symptoms were fever and cough; even among neonates 30 . Cough was experienced by the majority of patients, 10‐12,14,15,19,21‐93 it was mainly dry, but was sometimes followed by productive cough in moderately severe cases 19 . There may be upper airway symptoms, such as nasal congestion, rhinitis, and sore throat 19 .…”

Section: Resultsmentioning

confidence: 99%

“…Pneumonia/CT findings: Many pediatric patients had COVID‐19 pneumonia 10,11,16,19‐24,26,28‐31,34,38,40,42‐44,47‐54,56,57,60,61,64,66,68,70‐72,74‐76,78‐87,90‐92,94,95,99,100,103,155 and thoracic computerized tomography (CT) scan showed multifocal or nodular consolidation with ground glass opacities 11,15,16,19,22,23,26‐30,33,34,39,42‐44,47‐50,52‐54,60,61,64,66,72,74,78‐81,83‐86,91,95,100,103,107,164,165 . More adult patients had all five lobes affected 33,166 ; the manifestations of the COVID‐19 pneumonia are diverse and our understanding of the spectrum of disease is changing rapidly.…”

Section: Resultsmentioning

confidence: 99%

Coronavirus global pandemic: An overview of current findings among pediatric patients

Perikleous

Tsalkidis

Bush

et al. 2020

Pediatric Pulmonology

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Background The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) epidemic has been emerged as a cardinal public health problem. Children have their own specific clinical features; notably, they seem to be escaping the severe respiratory adverse effects. The international scientific community is rapidly carrying out studies, driving to the need to reassess knowledge of the disease and therapeutic strategies. Aim To assess the characteristics of COVID‐19 infected children worldwide of all ages, from neonates to children and adolescents, and how they differ from their adult counterparts. Search Strategy An electronic search in PubMed was conducted, using combinations of the following keywords: coronavirus, SARS‐CoV‐2, COVID‐19, children. The search included all types of articles written in English between January 1, 2019 until August 15, 2020. Results The search identified 266 relevant articles. Children were mainly within family clusters of cases and have relatively milder clinical presentation compared with adults; children were reported to have better outcomes with a significantly lower mortality rate. Cough and fever were the most common symptoms while pneumonia was the cardinal respiratory manifestation of infected children. Laboratory results and thoracic imaging give varying results. Conclusions Children were mainly family cluster cases and usually presented with a mild infection, although cases presented with the multisystem inflammatory syndrome are becoming more apparent. Studies determining why the manifestations of SARS‐CoV‐2 infection are so variable may help to gain a better understanding of the disease and accelerate the development of vaccines and therapies.

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Severe Pneumonia Due to SARS-CoV-2 and Respiratory Syncytial Virus Infection: A Case Report

Cited by 12 publications

References 14 publications

Community-Onset Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Young Infants: A Systematic Review

Community-Onset Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Young Infants: A Systematic Review

Risk Factors for Severity in Children with Coronavirus Disease 2019

Coronavirus global pandemic: An overview of current findings among pediatric patients

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