Severe Right Ventricular Outflow Tract Obstruction Caused by Non-Hodgkin Lymphoma: Complete Regression after One Course of Bendamustine/Rituximab Therapy

Konstandin, Mathias; Korosoglou, Grigorios; Hosch, Waldemar; Hardt, Stefan E.; Katus, Hugo A.; Mereles, Derliz

doi:10.1016/j.echo.2010.09.005

Cited by 2 publications

(3 citation statements)

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“…In our case symptoms and laboratory results lead us to perform a transthoracic echocardiogram that showed a mediastinal mass determining RVOT compression and pericardial effusion. Previous case reports described the importance of TTE as first line imaging exam [9,[11][12][13][14] to address to the correct diagnosis. Sometimes due to the technique limitations [15] or to better distinguish between clot and tumor Transesophageal Echocardiogram (TEE) is necessary [16].…”

Section: Discussionmentioning

confidence: 99%

“…Sometimes due to the technique limitations [15] or to better distinguish between clot and tumor Transesophageal Echocardiogram (TEE) is necessary [16]. However more detailed techniques as angio-CT scan [9,11,13] or Magnetic Resonance Imaging [4,17] are mandatory to describe the mass and its relationship with the closer structures. Positron Emission Tomography (PET) has been showed to be a considerable technique to detect unapparent cardiac involvement [11,[18][19].…”

Section: Discussionmentioning

confidence: 99%

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Usefulness of transthoracic echocardiogram in management of cardiac involvement in large B-Cell lymphoma: a case report

Ruzzolini

Panetta

Evangelista

et al. 2015

Monaldi Arch Chest Dis

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Usefulness of transthoracic echocardiogram in management of cardiac involvement in large B-Cell lymphoma: a case report

Ruzzolini

Panetta

Evangelista

et al. 2015

Monaldi Arch Chest Dis

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“…Mediastinal tumors (Figure ), typically lymphomas, can theoretically cause compression of all cardiac structures. However, due to mediastinal anatomy most case reports describe compression of the RVOT . Hence, these cases do not report classical tamponade physiology and the clinical picture is rather that of right‐sided heart failure.…”

Section: Extra‐cardiac Causes Of Tamponadementioning

confidence: 99%

When appearances deceive: Echocardiographic changes due to common chest pathology

et al. 2018

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Most indications for performing echocardiography focus on the evaluation of properties intrinsic to the heart. However, numerous extra‐cardiac conditions indirectly convey changes to the echocardiographic appearance through alterations in the governing physiology. Pulmonary embolism increases pulmonary arterial pressure if a sufficient cross‐sectional area of the pulmonary vascular bed is occluded. This may result in dilatation of the right ventricle and, in severe cases, concomitant early diastolic septal collapse into the left ventricle. Acute respiratory failure has been shown to yield a similar echocardiographic appearance in experimental conditions due to the resultant pulmonary vasoconstriction. Echocardiography in the presence of pulmonary disease can reveal underlying cardiac pathologies such as pulmonary hypertension that contribute to the clinical severity of respiratory distress. Positive pressure ventilation affects preload, afterload, and compliance of both ventricles. The echocardiographic net result cannot be uniformly anticipated, but provides information on the deciding physiology or pathophysiology. Mediastinal pathology including tumors, herniation of abdominal content, and pleural effusion can often be visualized directly with echocardiography. Mediastinal pathologies adjacent to the heart may compress the myocardium directly, thus facilitating echocardiographic and clinical signs of tamponade in the absence of pericardial effusion. In conclusion, many pathologies of extra‐cardiac origin influence the echocardiographic appearance of the heart. These changes do not reflect properties of the myocardium but may well be mistaken for it. Hence, these conditions are essential knowledge to all physicians performing echocardiography across the spectrum from advanced cardiological diagnostics to rapid point‐of‐care focused cardiac ultrasonography.

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Severe Right Ventricular Outflow Tract Obstruction Caused by Non-Hodgkin Lymphoma: Complete Regression after One Course of Bendamustine/Rituximab Therapy

Cited by 2 publications

References 15 publications

Usefulness of transthoracic echocardiogram in management of cardiac involvement in large B-Cell lymphoma: a case report

Usefulness of transthoracic echocardiogram in management of cardiac involvement in large B-Cell lymphoma: a case report

When appearances deceive: Echocardiographic changes due to common chest pathology

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