Severe SARS-CoV-2 infection in critical care

Fernández‐Sarmiento, Jaime; Acevedo, Lorena; Mulett, Hernando; Bastidas, Sarah; Sarta, Mauricio; Chacón, Shayl; Bejarano-Quintero, Ana María; Mizar, Orlanzo; Perez, Andrea; Uribe-Londoño, Juanita

doi:10.1016/j.tacc.2020.07.002

Cited by 4 publications

(5 citation statements)

References 56 publications

(110 reference statements)

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“…Just like MERS- CoV and SARS-CoV-1 infections, a comparatively greater proportion of Covid-19 patients may also develop gastro-intestinal symptoms such as diarrhoea . SARS-CoV-2 uniquely targets the lower airways (17) where it causes destruction of pneumocytes with infiltrating inflammation (18) . Other clinical features include loss of smell and taste.…”

Section: Clinical Featuresmentioning

confidence: 99%

Covid-19 and its implications for the provision of gynecological services globally

Khan

Mahmood²,

Konje

2022

European Journal of Obstetrics & Gynecology and Reproductiv

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Section: Clinical Featuresmentioning

confidence: 99%

Covid-19 and its implications for the provision of gynecological services globally

Khan

Mahmood²,

Konje

2022

European Journal of Obstetrics & Gynecology and Reproductiv

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“…However, this test is not considered the only tool to support diagnosis of acute infection because of the variability in the time for the seroconversion or the detection of antibodies against SARS-CoV-2 (6,43). The serological assay may be helpful in the case of an individual with a high likelihood of infection whose molecular diagnosis and antigen test show false-negative results (6,49,50). Unlike adults, the seroconversion rate can be lower among infected children (51,52), which suggests a weaker seroconversion in asymptomatic cases and slight forms of COVID-19 (43).…”

Section: Diagnosismentioning

confidence: 99%

“…Special attention must be given to adequate nutritional support and temperature control. Table 1 summarizes respiratory management in children (49,77). (49,77).…”

Section: Treatmentmentioning

confidence: 99%

COVID-19 in Children: Respiratory Involvement and Some Differences With the Adults

Hernández

Orozco

2021

Front. Pediatr.

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The coronavirus disease 2019 (COVID-19) represents a health problem with multidimensional impacts and heterogeneous respiratory involvement in children, probably due to the interaction between different and complex mechanisms that could explain its variable degrees of severity. Although the majority of reports reveal that children develop less severe cases, the number of patients is increasing with more morbidity. Most serious respiratory manifestations are acute respiratory distress syndrome (ARDS) and pneumonia. By understanding the key aspects that can be used to differentiate between pediatric and adult respiratory compromise by COVID-19, we can improve our knowledge, and thus decrease the negative impact of the disease in the pediatric population. In this mini review, we summarize some of the mechanisms and findings that distinguish between adult and pediatric COVID-19 and respiratory involvement, taking into account some issues related to the physiopathology, diagnosis, clinical and paraclinical presentation, severity, treatment, and control of the disease.

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“…In this issue of TACC, Fernandez-Sarmmiento and Colleagues [ 16 ] present a comprehensive review of SARS-CoV-2 infection, analyzing epidemiology, pathophysiology, clinical scenario and management options, with special emphasis on a checklist and protocol for airway management and a comprehensive overview on mechanical ventilation and respiratory support options. Alves Bersot and the Brazilian group [ 17 ] discuss also in this issue the physiology of prone positioning and the use of this approach for COVID-19 pneumonia.…”

Section: The Covid-19 Challenge and The Quality Of Researchmentioning

confidence: 99%