Sex and Body Mass Index Correlate With Western Ontario and McMaster Universities Osteoarthritis Index and Quality of Life Scores in Knee Osteoarthritis

Elbaz, Avi; Debbi, Eytan M.; Segal, Ganit; Haim, Amir; Halperin, Nahum; Agar, Gabriel; Mor, Amit; Debi, Ronen

doi:10.1016/j.apmr.2011.05.009

Cited by 54 publications

(51 citation statements)

References 18 publications

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“…FE stress results for a person with a healthy knee and a body mass index greater than 42 kg/m 2 indicate that permanent damage to the cartilage can occur if repeated exercise is carried out, especially where the patient's body mass is an inherent part of the exercise. This agrees with the results from large scale studies on the correlation between body mass index and osteoarthritis [27,29,30]. Ideally, clinically obese people should exercise where the body mass has little impact on the knee joint, for example, by using an exercise bicycle.…”

Section: Discussionsupporting

confidence: 81%

“…Several finite element models of the patellar femoral compartment of the knee joint have been created to investigate the link between patellar femoral stress and knee pain [21], relationships between shape and function [22], implant design and outcome [23][24][25][26][27], and the influence of femoral internal and external rotation on patellar femoral cartilages [28]. To our knowledge, no study has investigated the effect of knee joint contact stresses following an ACI.…”

Section: Discussionmentioning

confidence: 99%

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Stress in the Patella Following Autologous Chondrocyte Implantation - A Finite Element Study

Walker¹,

Cheah²,

Ingle³

et al. 2013

J Comput Sci Syst Biol

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Bovine patella cartilage shows signs of damage and cell death when subjected to a compressive cyclic load of 6 MPa, which results in a shear stress of 5.6 MPa. The aim of this research was to investigate the effect of activities of daily living (descending stairs, bicycling and deep flexion) on the contact stresses in the patellofemoral compartment following an articular chondrocyte implantation. A finite element (FE) model of the patellar femoral joint was created and dynamic non-linear analyses were carried out for this purpose. A shear stress of 5.6 MPa was used as the threshold that cartilage can tolerate without resulting in damage. The FE model was verified numerically.Our results show that, for a 70 kg individual at 50% recovery, (i) contact stress in the patella is 11% higher than that in the femur; (ii) shear stress in the host cartilage reaches 4.75 MPa at 50° of flexion; (iii) shear stress in the patella host cartilage is twice that in a healthy cartilage during deep flexion approaching 70°; (iv) maximum shear stress value was 2.75 MPa during cycling at 60% load; (v) stress shielding still occurs through the host cartilage even when the implanted cartilage reaches 97.5% the Young's modulus of a healthy cartilage. Based on these results, (i) using an exercise bicycle is recommended for rehabilitation; (ii) deep knee flexion should be avoided; (iii) obese people with a BMI of over 42 kg/m 2 should not undertake vigorous weight-bearing exercises involving deep knee flexion. Stress in the Patella

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Section: Discussionsupporting

confidence: 81%

Section: Discussionmentioning

confidence: 99%

Stress in the Patella Following Autologous Chondrocyte Implantation - A Finite Element Study

Walker¹,

Cheah²,

Ingle³

et al. 2013

J Comput Sci Syst Biol

View full text Add to dashboard Cite

show abstract

“…Increased mechanical stress [5,6] may explain the association between BMI and knee pain and activity limitations. Overweight increases the load on the knees during weight bearing activities, which may lead to pain and activity limitations.…”

Section: Discussionmentioning

confidence: 99%

“…Overweight and depressed mood are more common in knee osteoarthritis (OA) than in the general population [1][2][3], and are both positively associated with pain and activity limitations [4][5][6][7][8][9][10][11][12][13]. There is growing evidence that overweight, as indicated by body-mass index (BMI) ≥ 25 kg/m 2 , and depressed mood are interrelated [14,15], and that common biological and psychological mechanisms underlie the development of both overweight and depressed mood [16].…”

Section: Introductionmentioning

confidence: 99%

Depression and Perceived Quality of Sleep in Older Adults with Knee Osteoarthritis

Park¹,

Kim²

2017

J Korean Gerontol Nurs

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Background: Body-mass index (BMI) and depressed mood are both positively associated with pain and activity limitations in knee osteoarthritis (OA), and are interrelated. The aims of the present study were: 1) to assess whether BMI and depressed mood are independently associated with knee pain and activity limitations; and 2) to compare the relative contributions of BMI and depressed mood to knee pain and activity limitations. Methods: A cross-sectional study in 294 patients with clinical knee OA. Regression analyses were performed with knee pain or activity limitations (self-reported and performance-based) as dependent variables, and BMI and depressed mood as independent variables. All analyses were adjusted for age, gender, marital status, education level, radiographic OA and comorbidity. Dominance analyses were performed to examine the relative contributions of BMI and depressed mood to knee pain and activity limitations. Results: BMI and depressed mood were positively and independently associated with knee pain and activity limitations. BMI and depressed mood explained small parts (3.0% and 2.3%, respectively) of variance in knee pain. BMI explained a substantial part of variance in both self-reported (9.8%) and performance-based (20.4%) activity limitations, while depressed mood explained a small part of variance (3.1% in self-reported and 2.6% in performance-based activity limitations). Conclusions: In patients with knee OA both BMI and depressed mood seem to be independently associated with knee pain and activity limitations. The contribution of BMI to activity limitations is most substantial, thereby offering a relevant target for interventions.

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“…A number of researches considered several aspects related to muscle function, such as strength and aerobic capacity as well as other clinical aspects, such as pain, stifness, range of motion of the knee, and WOMAC in patients with OA [14][15][16][17][18][19][20].…”

Section: Discussionmentioning

confidence: 99%

Effect of Nonpharmacological Therapies on Pain and Health Perception in Patients with Knee Osteoarthritis

Lizis¹,

Kobza²,

Mańko³

et al. 2017

Pain Relief - From Analgesics to Alternative Therapies

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Objective: Comparing the eiciency of ultrasound therapy (US) versus extracorporeal shock wave therapy (ESWT) on pain and perceived health in men with bilateral knee osteoarthritis (OA). Design: A pilot randomized trial with concealed allocation, assessor blinding and intention-to-treat analysis was conducted.Participants: 60 men, 44-66 years old were randomized to an experimental (US) and a control (ESWT) group. Intervention: The participants in both groups atended 5-week treatments. The experimental group received continuous US and a series of 10 treatments two times per week. The control group received 5 ESWT treatments once per week. Outcome measures:The primary outcome was visual analogue scale (VAS) pain ratings. The secondary outcome measured perceived health using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). The examinations were taken before and after the treatment. Results: After 5-week treatment the experimental group had signiicantly worse scores than the control group on the VAS for pain, and on the WOMAC for perceived health. Conclusion: Patients with knee OA can achieve signiicant beter health beneits caused by ESWT than by US.

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Sex and Body Mass Index Correlate With Western Ontario and McMaster Universities Osteoarthritis Index and Quality of Life Scores in Knee Osteoarthritis

Cited by 54 publications

References 18 publications

Stress in the Patella Following Autologous Chondrocyte Implantation - A Finite Element Study

Stress in the Patella Following Autologous Chondrocyte Implantation - A Finite Element Study

Depression and Perceived Quality of Sleep in Older Adults with Knee Osteoarthritis

Effect of Nonpharmacological Therapies on Pain and Health Perception in Patients with Knee Osteoarthritis

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