Sex Differences in the Association of Regional Fat Distribution with the Severity of Obstructive Sleep Apnea

Simpson, Laila; Mukherjee, Sutapa; Cooper, Matthew N.; Ward, Kim; Lee, Jessica D.; Fedson, Annette C.; Potter, Jane; Hillman, David R.; Eastwood, Peter R.; Palmer, Lyle J.; Kirkness, Jason P.

doi:10.1093/sleep/33.4.467

Cited by 172 publications

(120 citation statements)

References 33 publications

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“…In addition, there is a relationship between obstructive sleep apnea and resistance to leptin, a hormone derived from adipose tissue that is important in weight control and energy expenditure (27) . Another important aspect, is that the SD generally have a higher prevalence in males (26) , However, we found no difference in the frequency distribution, besides the scales scores were also similar between the genders. The small number of male patients evaluated in the study (22%) may have been responsible for the result.…”

Section: Discussioncontrasting

confidence: 55%

“…The presence of central obesity increases the accumulation of visceral fat, causing instability or even collapse of the upper airways (25,26) . The obesity and the SD have congruent pathophysiology, one-night sleep deprivation significantly affects ghrelin and cortisol levels, favoring the reduction of energy expenditure and increasing the sensation of hunger.…”

Section: Discussionmentioning

confidence: 99%

“…The preoperative evaluation of SD is of paramount importance, requiring more attention to patients with OSAHS in the pre, intra and postoperative management of these patients (23)(24)(25)(26)(27) . Caution should be exercised when administering drugs used as anesthetics and analgesics, which may induce hypotonia of the dilator muscles of the pharynx, and also depress the respiratory center, causing hypopnea and desaturation.…”

Section: Discussionmentioning

confidence: 99%

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Prevalence of sleep disorders in obese before bariatric surgery.

Carlos¹,

Oliver²,

Cruz³

et al. 2020

mtprehabjournal

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Introduction:The prevalence of sleep disorders (SD) has increased significantly in recent decades in parallel to the worldwide obesity epidemic. The presence of SD provides an increased risk of postoperative complications, requiring greater care in these patients. The gold standard for evaluation and diagnosis of SD is polysomnography, but it is an expensive and highly complex exam, making the questionnaires and scales more accessible for diagnosis and screening. Objectives: To evaluate the presence of SD and to analyze the influence of anthropometric measures on the scores of the Epworth Sleepiness Scale (ESS), snoring (ERS) and Stanford Sleepiness Scale (SSS) in obese patients. Method: An observational, cross-sectional study performed from August 2015 to August 2016. The patients in the preoperative group of bariatric surgery of the University Hospital were submitted to anthropometric evaluation and application of the ESS, ERS and SSS during the preoperative physiotherapy evaluation. Results: Were evaluated 100 obese (78 women), mean age of 41.4±10.7 years and BMI of 46.1±7.8kg/m 2 . SD were identified in 25% by ESS and 21% by SSS of obese. There were no differences between genders for the scales scores. The score of the ERS correlated itself with waist (r=0.20, p=0.04) and neck (r=0.33, p=0.001) circumferences. Conclusion: The use of scales for diagnosis of SD is useful in the follow-up of the preoperative of bariatric surgery and our study found that 25% of patients present daytime somnolence. We also observed the influence of waist and neck circumferences on increasing snoring scale.

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Section: Discussioncontrasting

confidence: 55%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Prevalence of sleep disorders in obese before bariatric surgery.

Carlos¹,

Oliver²,

Cruz³

et al. 2020

mtprehabjournal

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“…A radiologic imaging study as magnetic resonance showed the greater soft tissue loading on the airway in men [38]. However, other study, a dual energy X-ray absorptiometry, reported a direct influence of neck fat on upper airway patency in women [32]. A recent study in Turkey reported that NC was of greater value than waist circumference in men but not in women [23].…”

Section: Discussionmentioning

confidence: 98%

What can anthropometric measurements tell us about obstructive sleep apnoea?

Yılmaz

Akcaalan

2017

Folia Morphol

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“…Была выяв-лена прямая связь между увеличением локального отложения жира вокруг глотки, окружающих мягких парафарингеальных тканях верхних дыхательных путей и степенью тяжести СОАГС [32]. Показано, что ожирение вокруг грудной клетки и живота вы-зывает снижение объема легких и сужение глотки, воздействуя на глоточную проходимость и разви-тие СОАГС [33]. Особое внимание как предиктору СОАГС уделяется распределению жира в области шеи [34].…”

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ETHNOS END OBSTRUCTIVE APNEA/HYPOPNEA SYNDROME (foreign literature review)

Golokov¹,

Shnayder²,

Nikolaeva³

et al. 2017

BCCM

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Войно-Ясенецкого» Минздрава России, Россия, 660022, Красноярск, ул. Партизана Железняка, 1, e-mail: naschnaider@yandex Россия, 677005, Якутск, ул. Свердлова, 1/2, e-mail: mshmvdrsy@mail.ru Реферат. Синдром обструктивного апноэ/гипопноэ сна -это распространенный, опасный для жизни тип апноэ сна, который обусловлен обструкцией верхних дыхательных путей. Это состояние характеризуется повторяющимися паузами в дыхании во время сна, несмотря на усилия дыхательных мышц и, как прави-ло, связано с уменьшением насыщения крови кислородом. Интерес исследователей к данной проблеме связан с тем, что синдром обструктивного апноэ/гипопноэ сна является неблагоприятным последствием развития сердечно-сосудистых заболеваний и внезапной смерти. Цель исследования -анализ совре-менных этнических данных по проблеме распространенности, факторах риска, патогенезе, фенотипах, диагностике и лечению синдрома обструктивного апноэ/гипопноэ сна. Материал и методы. Приведен обзор исследований по изучению роли этноса в данном заболевании. Результаты и их обсужде-ние. Представлены данные по распространенности, фенотипическим отличиям, подходам к диагностике и лечению синдрома обструктивного апноэ/гипопноэ сна в разных этнических группах стран Америки, Ев-ропы и Азии. Выводы. Несмотря на сопоставимую распространенность синдрома обструктивного апноэ/ гипопноэ сна в разных этнических группах, патогенетические факторы, приводящие к развитию заболева-ния, многообразны и широко варьируют. Их отдельное доминирование или сочетанная представленность, вероятно, имеют генетическую основу, а фенотипы и степень тяжести синдрома обструктивного апноэ/ гипопноэ сна различны между популяциями. Доступные скрининговые клинические и инструментальные исследования пациентов с синдромом обструктивного апноэ/гипопноэ сна разных этнических групп по-зволяют выявить степень риска развития данной патологии, провести своевременную профилактику и коррекцию. Ключевые слова: обструктивное апноэ сна, гипопноэ, этнос, фенотип, факторы риска, обзор. Russia, 677005, Yakutsk, Sverdlov str., 1/2, Abstract. The syndrome of obstructive sleep apnea/hypopnea is a common, life-threatening type of sleep apnea, which is caused by obstruction of the upper respiratory tract. This condition is characterized by repeated pauses in breathing during sleep, despite the efforts of respiratory muscles. It is usually associated with a decrease in blood oxygen saturation. The researchers are interested in this problem due to the fact that obstructive sleep apnea/hypopnea syndrome is an adverse consequence of cardiovascular diseases and sudden death. Aim. Analysis of modern data on prevalence, risk factors, pathogenesis, phenotypes, diagnosis and treatment of obstructive sleep apnea/hypopnea syndrome has been performed. Material and methods. The article provides an overview of research on the role of ethnos in development of this disease. Results and discussion. The data on prevalence, phenotypic differences, approaches to diagnostics and treatment of obstructive sleep apnea/hypopnea syndrome in...

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Sex Differences in the Association of Regional Fat Distribution with the Severity of Obstructive Sleep Apnea

Cited by 172 publications

References 33 publications

Prevalence of sleep disorders in obese before bariatric surgery.

Prevalence of sleep disorders in obese before bariatric surgery.

What can anthropometric measurements tell us about obstructive sleep apnoea?

ETHNOS END OBSTRUCTIVE APNEA/HYPOPNEA SYNDROME (foreign literature review)

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