2020
DOI: 10.1016/j.bbr.2020.112839
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Sex differences in the effects of a combined behavioral and pharmacological treatment strategy for cocaine relapse prevention in an animal model of cue exposure therapy

Abstract: Brief interventions of environmental enrichment (EE) or the glycine transporter-1 inhibitorOrg24598 administered with cocaine-cue extinction training were shown previously to inhibit reacquisition of cocaine self-administration in male rats trained to self-administer a moderate 0.3 mg/kg dose of cocaine. Determining how EE and Org24598 synergize in combination in an animal model of cue exposure therapy is novel. Important changes made in this investigation were increasing the cocaine training dose to 1.0 mg/kg… Show more

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Cited by 2 publications
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References 92 publications
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