“…In contrast to the sex-related dichotomy observed in response to nutritional stressors, when faced with a robust stressor such as AT 1 antagonism (Loria et al, 2007a;Loria et al, 2007b;Saez et al, 2007;Salazar et al, 2008), severe protein restriction (Woods et al, 2001), or chronic reductions uterine perfusion pressure (Ojeda et al, 2007a;Alexander, 2003) both male and female fetuses are affected similarly in utero. Nonetheless a dichotomy emerges later in life with females being less impacted by their suboptimal in utero experience (Loria et al, 2007a;Loria et al, 2007b;Saez et al, 2007;Salazar et al, 2008).…”