Sex differential association of dermatomyositis with Sjögren syndrome

Tseng, Chia‐Chun; Chang, Shun‐Jen; Tsai, Wen‐Chan; Ou, Tsan‐Teng; Wu, Chuan-Chun; Sung, Wan‐Yu; Hsieh, Ming‐Chia; Yen, Jeng‐Hsien

doi:10.1503/cmaj.160783

Cited by 11 publications

(8 citation statements)

References 53 publications

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“…The skin is one of the tissues which are commonly affected by autoimmune disorders (17). There are several different types of skin-related autoimmune disorders including scleroderma, psoriasis, dermatomyositis, and autoimmune bullous disorders (11)(12)(13). The incidence and severity of autoimmune skin diseases may vary depending on the type of skin disorders, gender, age, and ethnicity (19,20).…”

Section: Discussionmentioning

confidence: 99%

Association of Bacterial Vaginosis and Skin Disorders in Patients with Autoimmune Antibody Positivity

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Dönmez

2021

Gynecol Obstet Reprod Med

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OBJECTIVE: To investigate the association of bacterial vaginosis and skin disorders in patients with autoimmune antibody positivity. STUDY DESIGN: This retrospective study consisted of 80 patients with autoimmune antibody positivity. All patients were evaluated for the presence of bacterial vaginosis and skin disorders. Cervicovaginal smears were used for the definitive diagnosis of bacterial vaginosis. RESULT: We found bacterial vaginosis in 13.75% (11/80) of the cases. 1 (9.1%) and 10 (90.9%) cases had skin disorders in bacterial vaginosis positive and negative groups respectively (p=0.531). CONCLUSION: There is no relationship between bacterial vaginosis and the presence of skin disorders in patients with autoimmune antibody positivity.

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Section: Discussionmentioning

confidence: 99%

Association of Bacterial Vaginosis and Skin Disorders in Patients with Autoimmune Antibody Positivity

Beksaç

Dönmez

2021

Gynecol Obstet Reprod Med

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“…Patients having a catastrophic illness certificate for pSS were defined as a SS case. The definition of SS has been widely reported in previous NHIRD studies [9–11]. The present study was approved by the Chang Gung Medical Foundation Institutional Review Board (No.…”

Section: Methodsmentioning

confidence: 99%

The effect of pilocarpine on dental caries in patients with primary Sjögren’s syndrome: a database prospective cohort study

et al. 2019

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BackgroundPrimary Sjögren’s syndrome (pSS) is associated with dental caries. Pilocarpine, a salivary stimulant, can improve the amount and flow rate of saliva in patients with pSS. This study aimed to assess whether the risk of dental caries decreases with the use of pilocarpine in patients with pSS.MethodsFor this prospective cohort study, we identified pSS patients from the catastrophic illnesses registry of the National Health Insurance Research Database of Taiwan between 2009 and 2013. We divided participants into pilocarpine and non-user groups based on the pilocarpine prescriptions available during the first 3-month follow-up. The primary endpoint was dental caries. The secondary endpoints were periodontitis and oral candidiasis. We compared the risk of these oral manifestations using the Cox proportional hazard model.ResultsA total of 4973 patients with new-onset pSS were eligible for analysis. After propensity score matching, we included 1014 patients in the pilocarpine group and 2028 patients in the non-user group. During the mean follow-up of 2.6 years, the number of events was 487 in the pilocarpine group (48.0%) and 1047 in the non-user group (51.6%); however, the difference was not significant (hazard ratio [HR] 0.93, 95% confidence interval [CI] 0.82 to 1.06). Furthermore, there was no significant difference between groups regarding risk of periodontitis (HR 0.91, 95% CI 0.81 to 1.03) and oral candidiasis (HR 1.16, 95% CI 0.70 to 1.94).ConclusionPilocarpine may have no protective effect on dental caries, periodontitis, or oral candidiasis in patients with pSS.

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“…Although gender bias reports are conflicted, recent studies indicate psoriasis is significantly more severe, along with more frequent ocular complications, in males (176). Similarly, although females are at greater risk of dermatomyositis (139), Tseng et al found that males with dermatomyositis were more likely to experience SS when compared to females (177). Dermatomyositis has a slightly higher female predisposition; however, this declines naturally with age (178).…”

Section: Dermatologicalmentioning

confidence: 99%

Epidemiology of Ocular Manifestations in Autoimmune Disease

2021

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The global prevalence of autoimmune diseases is increasing. As a result, ocular complications, ranging from minor symptoms to sight-threatening scenarios, associated with autoimmune diseases have also risen. These ocular manifestations can result from the disease itself or treatments used to combat the primary autoimmune disease. This review provides detailed insights into the epidemiological factors affecting the increasing prevalence of ocular complications associated with several autoimmune disorders.

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Sex differential association of dermatomyositis with Sjögren syndrome

Cited by 11 publications

References 53 publications

Association of Bacterial Vaginosis and Skin Disorders in Patients with Autoimmune Antibody Positivity

Association of Bacterial Vaginosis and Skin Disorders in Patients with Autoimmune Antibody Positivity

The effect of pilocarpine on dental caries in patients with primary Sjögren’s syndrome: a database prospective cohort study

Epidemiology of Ocular Manifestations in Autoimmune Disease

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