Sex distribution in cardiac myxomas

Hi, Dong; Yoon, Anthony; Roberts, William C.

doi:10.1016/s0002-9149(02)02540-7

Cited by 53 publications

(12 citation statements)

References 22 publications

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“…Our results are in agreement with those who noted a higher percentage of female patients suffering from a myxoma. A recent analysis of multiple surgical series including 1195 individuals with myxomas revealed that 67% were female and 33% were male [4]. Patients with myxoma (Carney) complex are generally younger and more often male in comparison with patients with sporadic myxomas [5, 6].…”

Section: Discussionmentioning

confidence: 99%

Primary Cardiac Tumours: A Single-Center 41-Year Experience

2012

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Primary cardiac tumours are extremely rare with the most commonest being left atrial myxomas. In general, surgical resection is indicated, whenever the tumour formation is mobile and embolization can be suspected. Within 17280 patients receiving heart surgery at the Innsbruck Medical University, 78 patients (0.45%) underwent tumourectomy of primary cardiac tumours. The majority of patients (63) suffered from a left or right atrial myxoma, 12 showed a papillary fibroelastoma of the valves at echocardiographical or histological examination, 1 suffered from a hemangioma, 1 from a chemodectoma, and another one from a rhabdomyosarcoma. The mean age of cardiac tumour patients was 54.29 ± 13.28 years (ranging from 18 to 83 years). 67.95% of the patients were female and 32.05% were male. The majority of tumours were found incidentally; 97.44% of the patients showed no tumour recurrence.

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Section: Discussionmentioning

confidence: 99%

Primary Cardiac Tumours: A Single-Center 41-Year Experience

2012

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“…They are three times more common in females and 90% are diagnosed in the fourth to sixth decades of life [6,10]. They are rarely seen in children, in whom they constitute 15% of cardiac tumors [6,11,12].…”

Section: Cardiac Myxomasmentioning

confidence: 99%

Molecular Basis of Cardiac Myxomas

Singhal

Luk

Rao

et al. 2014

IJMS

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Cardiac tumors are rare, and of these, primary cardiac tumors are even rarer. Metastatic cardiac tumors are about 100 times more common than the primary tumors. About 90% of primary cardiac tumors are benign, and of these the most common are cardiac myxomas. Approximately 12% of primary cardiac tumors are completely asymptomatic while others present with one or more signs and symptoms of the classical triad of hemodynamic changes due to intracardiac obstruction, embolism and nonspecific constitutional symptoms. Echocardiography is highly sensitive and specific in detecting cardiac tumors. Other helpful investigations are chest X-rays, magnetic resonance imaging and computerized tomography scan. Surgical excision is the treatment of choice for primary cardiac tumors and is usually associated with a good prognosis. This review article will focus on the general features of benign cardiac tumors with an emphasis on cardiac myxomas and their molecular basis.

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“…They occur mainly in middle-aged population with average age 50-60 years, affecting women more frequently than men. The female to male sex ratio in left atrial cardiac myxomas was found to be 2:1 while in right atrial cardiac myxomas it was 0.75:1 [8,9].…”

Section: Epidemiologymentioning

confidence: 87%