Sex-related differences in immune response and survival rate of broiler chickens

Leitner, G.; Heller, E. D.; Friedman, Aharon

doi:10.1016/0165-2427(89)90035-4

Cited by 63 publications

(44 citation statements)

References 16 publications

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“…These results confirm those of Heller et d. (1981), who found that antibody responses to E. coli were earlier in chicks from the Sinai breed than in Leghorns. Also in several cases, anti-body titers of females were higher than those of males, confirming previous observations (Leitner et al, 1989). The differences in the immune system's maturation in lines selected for only three generations indicate genetic variation for the development of the immune response to E. coli, in both, the rate of response and in magnitude of the titers.…”

Section: Discussionsupporting

confidence: 84%

“…Escherichia coli Serotypes O78:K80 and 02:K1 were used for the immunizations, challenge tests, and ELISA, as described in Leitner et al (1989). Antibody production and survival rate after challenge with pathogenic E. coli, with or without prevaccination, was tested after the first and second selection cycles.…”

Section: Antigens Used For Immunization and Challenge Testsmentioning

confidence: 99%

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Replicated Divergent Selection of Broiler Chickens for High or Low Early Antibody Response to Escherichia coli Vaccination

et al. 1992

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Four sublines of broiler chickens were selected from a base population for three generations for high or low antibody response to vaccination with Escherichia coli at 10 days of age. Two sublines were selected for a high response (HC) and two for a low response (LC). Realized heritability estimates over three generations of selection for each pair of replicated lines averaged .23 in HC lines and .32 in LC lines. No correlated response in the important production trait, body weight at marketing age, was observed. The ability to survive pathogenic E. coli challenge with or without prevaccination showed no differences between the lines in the unvaccinated chicks, although following vaccination there was higher mortality and morbidity in the LC lines. These data suggest that the use of antibody response in young chicks to E. coli vaccine may be a useful genetic indication of more general disease resistance.

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Section: Discussionsupporting

confidence: 84%

Section: Antigens Used For Immunization and Challenge Testsmentioning

confidence: 99%

Replicated Divergent Selection of Broiler Chickens for High or Low Early Antibody Response to Escherichia coli Vaccination

et al. 1992

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“…There are conflicting reports about the effect of gender on immune response, while some reports have demonstrated similar antibody response for both genders (Klingensmith et al 1983;van der Zijpp et al 1986), others showed superior response in females (Leitner et al 1989). In this study, we noted that the females had a higher antibody response against ND vaccinations.…”

Section: Immune Responsesupporting

confidence: 59%

Response to withdrawal of vitamin and trace mineral premixes from finisher diet in broiler chickens under the hot and humid tropical condition

Mochamat

Zulkifli

Farjam

et al. 2017

Italian Journal of Animal Science

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This study was conducted to assess the effects of omitting vitamin (VIT) and trace mineral (TRM) premixes from the finisher diet on growth performance, antibody production against Newcastle disease (ND) vaccination, leg bone strength and incidence of foot pad dermatitis (FPD) in male and female broiler chickens. Birds were raised on floor pens in a naturally ventilated house using wood shavings as litter. Commencing from day 21, equal number of male and female birds were subjected to one of four VIT and TRM premixes withdrawal treatments as follows: (i) withdrawal from 21 to 42 days, (ii) withdrawal from 28 to 42 days, (iii) withdrawal from 35 to 42 days, and (iv) no withdrawal (control). In comparison to the control group, feed intake, body weights, feed conversion ratios and antibody responses to Newcastle disease vaccination were not affected by any of the supplement withdrawal treatment. Male birds had lower antibody production and higher bone-breaking strength as compared to their female counterparts. Irrespective of gender, withdrawal of VIT and TRM premixes from 21 to 42, and 28 to 42 days adversely affected bone-breaking strength. In conclusion, VIT and TRM premixes can be removed from the diet of male and female broiler chickens from 21 to 42 days without any adverse effects on growth performance, mortality, antibody response and incidence of foot pad dermatitis. However, bone-breaking strength was adversely affected by the withdrawal of VIT and TRM premixes for more than seven days. ARTICLE HISTORY

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“…In vitro peripheral-blood-lymphocyte (PBL) proliferative responses of vaccinated turkeys were studied according to Leitner et al (1989) and Lee et al (1991) with some modifications. PBLs, separated by low speed centrifugation (50 & 15 min) of heparinized whole blood, were cultured (10 6 cells/well) in 96-well tissue culture cluster plates (Costar, Cambridge, MA, USA) in 100 ^1 RPMI medium, supplemented with L-glutamine (2 mM), 50 units of penicillin and 50 fig streptomycin/ ml (all from Sigma, St Louis, MO, USA).…”

Section: Lymphocyte Blastogenesis-by-antigen Testmentioning

confidence: 99%

Vaccination of turkey poults against pathogenicEscherichia coli

1997

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SUMMARYA vaccine made of bacterial membranes which form vesicles has been developed in our laboratory and found to be effective in protecting chickens against challenge with pathogenic E. coli. In the present study we monitored maternal anti-5. coli antibody in turkey poults and found that although at hatch the antibody titre was relatively high, it decreased gradually to a low level by 14 days of age and remained low up to 31 days of age. Both intramuscular and subcutaneous vaccination with membrane vesicles (MV) resulted in increased antibody titres. Poults with high antibody titres could survive challenge with the pathogenic bacteria. Serum from vaccinated poults reduced E. coli bacterial growth rate when added to the growth medium at a high concentration, whereas serum from non-vaccinated poults did not. Lymphocytes from vaccinated poults responded with an increased rate of blastogenesis when MV was added to the cultures. Lymphocytes from non-vaccinated poults were not stimulated to blastogenesis. We concluded that MV can be used as a vaccine to render poults resistant to E. coli by evoking antibody production, stimulating the bacterial-lysis activity of complement, stimulating T cells to proliferate and stimulating cytotoxic T cells involved in disease resistance.

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Sex-related differences in immune response and survival rate of broiler chickens

Cited by 63 publications

References 16 publications

Replicated Divergent Selection of Broiler Chickens for High or Low Early Antibody Response to Escherichia coli Vaccination

Replicated Divergent Selection of Broiler Chickens for High or Low Early Antibody Response to Escherichia coli Vaccination

Response to withdrawal of vitamin and trace mineral premixes from finisher diet in broiler chickens under the hot and humid tropical condition

Vaccination of turkey poults against pathogenicEscherichia coli

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