Sexual practices and HPV infection in unvaccinated young adults

Abstract

The present study aimed to evaluate the association of genital and oral HPV infection among different sexual practices in both sexes. In total, 6388 unvaccinated men and women aged 16–25 years from all state capitals of Brazil were enrolled in through primary care services between September 2016 and November 2017. Genital and oral HPV genotyping was performed using the Roche Linear Array. Poisson regression analysis with robust variance was conducted to examine factors associated with overall HPV infection. A higher prevalence of genital HPV was found in women who practiced oral sex (57.85%) and in men who practiced all types of sex (65.87%). However, having more sexual partners and being younger were more important than the type of sex practiced. HPV 6 (7.1%) and 16 (10.5%) were significantly more prevalent in women who practiced oral sex, while HPV 6 (23.96%) and 11 (21.49%) were more prevalent in men who practiced anal sex. The type of sex was not associated with oral HPV prevalence. Genital and oral HPV infection were not associated by different sexual practices in the studied population.

Oral human papillomavirus (HPV) infection and HPV vaccination in an Australian cohort

“…We found that measures of sexual activity, such as increasing numbers of sex partners, were strongly associated with oral HPV infection; the strongest associations were seen with frequency of oral sex partners (both giving and receiving). This finding has been observed in other regions of the world 7‐9,14,20‐22 . Furthermore, we found that a previous diagnosis of a STI was associated with oral HPV infection, and in particular a previous diagnosis with herpes simplex.…”

“…This finding has been observed in other regions of the world. [7][8][9]14,[20][21][22] Furthermore, we found that a previous diagnosis of a STI was associated with oral HPV infection, and in particular a previous diagnosis with herpes simplex.…”

“…1,2 Recent research has shown that the rising incidence of OPC is likely caused by the increasing prevalence of oral human papillomavirus (HPV) infections acquired through oral sex. [3][4][5][6][7][8][9] Our recently published Australian data 10,11 and other studies of OPC have linked high number of lifetime sex partners with HPV-positive OPCs. [12][13][14] The HPV vaccine has been included in many national immunisation programs worldwide.…”

“…While other cancers related to smoking are decreasing, the incidence of oropharyngeal cancer (OPC) is increasing 1,2 . Recent research has shown that the rising incidence of OPC is likely caused by the increasing prevalence of oral human papillomavirus (HPV) infections acquired through oral sex 3‐9 . Our recently published Australian data 10,11 and other studies of OPC have linked high number of lifetime sex partners with HPV‐positive OPCs 12‐14 …”

Sexo Oral

“…Apesar do risco menor de transmissão quando comparado com o sexo penetrativo vaginal e anal, o sexo oral também é um meio importante de contágio de IST's. Há quatro formas de transmissão de doenças por meio do sexo oral ou contato oral: transmissão por contato direto com epitélio ou mucosa, cujos mais frequentes são os vírus, como HPV e herpes, destaca-se um aumento do risco de ocorrência de câncer de boca e orofaringe nas infecções por HPV oncogênicos (ANTONSSON et al, 2022;PAULI et al, 2022); através do sangue, em que na presença deste durante o sexo oral, podem ser transmitidos o HIV, a hepatite B, a hepatite C e a sífilis; através das secreções, pode ser transmitida a gonorreia e a Chlamydia; e ainda pela transmissão vertical: o vírus do HPV adquirido no canal de parto da mãe pode se estabelecer na cavidade oral do(a) filho(a), podendo, assim, ser transmitido, posteriormente, à parceria.…”