Sexuality in Huntington's disease

Schmidt, Eva; Bonelli, Raphael M.

doi:10.1007/s10354-007-0477-8

Cited by 35 publications

(10 citation statements)

References 36 publications

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“…In fact, symptoms of HSD were described by Professor Américo Negrette, a Venezuelan neurologist, in high frequency, in his seminal clinical contribution about HD 6 . Additionally, other publications about sexuality in HD, have demonstrated hypoactive sexual disorders 7 . In conclusion, psychosocial factors or specific brain lesion could be the cause of sexual dysfunction in patients with HD 8 .…”

Section: Discussionmentioning

confidence: 92%

Increased sexual arousal in patients with movement disorders

Teive

Moro

Moscovich

et al. 2016

Arq. Neuro-Psiquiatr.

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Increased of sexual arousal (ISA) has been described in different neurological diseases. The purpose of this study was present a case series of ISA in patients with movement disorders. Method Fifteen patients with different forms of movement disorders (Parkinson’s disease, Huntington’s disease, Tourette´s syndrome, spinocerebellar ataxia type 3), were evaluated in the Movement Disorders Unit of the Federal University of Paraná. Results Among Parkinson’s disease patients there were seven cases with different forms of ISA due to dopaminergic agonist use, levodopa abuse, and deep brain stimulation (DBS). In the group with hyperkinetic disorders, two patients with Huntington’s disease, two with Tourette’s syndrome, and four with spinocerebellar ataxia type 3 presented with ISA. Conclusions ISA in this group of patients had different etiologies, predominantly related to dopaminergic treatment or DBS in Parkinson’s disease, part of the background clinical picture in Huntington’s disease and Tourette’s syndrome, and probably associated with cultural aspects in patients with spinocerebellar ataxia type 3.

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Section: Discussionmentioning

confidence: 92%

Increased sexual arousal in patients with movement disorders

Teive

Moro

Moscovich

et al. 2016

Arq. Neuro-Psiquiatr.

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“…Although we did not consider reviews in our paper (as stated in the methodology), one, the most recent performed by Schmidt and Bonelli (2008), should be mentioned. This paper included only five original studies and only one of these selected patients based on genetic testing [27].…”

Section: Discussionmentioning

confidence: 99%

Sexual dysfunction in Huntington’s Disease — a systematic review

Szymuś

Bystrzyński

Kwaśniak-Butowska

et al. 2020

Neurol Neurochir Pol.

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Introduction. Huntington's Disease (HD) is a neurodegenerative disorder of which the main symptoms are motor, cognitive and behavioural problems sometimes including sexual dysfunction. Aim.To review the current knowledge on sexual dysfunction in HD.Methods. Databases of Pubmed and Scopus were searched. Only original studies performed after 1994 were included (from 1994 a genetic test = proven diagnosis).Results. 162 publications were found, but only nine met our established criteria. The majority of patients with HD suffer from sexual disorders. The most common are: hypoactive sexual disorder (53-83% of patients), hyperactive sexual disorder (6-30%), erectile (48-74%) and ejaculatory dysfunctions (30-65%), lubrication problems (53-83%), and orgasmic dysfunction (35-78%).Discussion. Results may be biased for several reasons e.g.: social taboos regarding sex lives, medications that affect sexual function, impaired self-awareness of patients, small study samples, a lack of standardised questionnaires, and a focus only on the presence of sexual problems without describing them.Conclusions. Sexual disorders in HD are common. This is a problem that is probably underestimated, both by patients/caregivers and physicians, who should focus more on these symptoms in order to improve patient quality of life.

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“…Both temporal and frontotemporal dementias (Lewy body dementia, Pick's disease), or either of them, can exhibit socially inappropriate behaviors (including sexual ones) [24]. Hypersexual behavior, pedophilia, promiscuity, and indecent exposure have been described in Huntington's disease [27]. The involvement of the medial striatum of the basal ganglia in this disease explains the prevalence of ISB [24].…”

Section: Epidemiology and Cause Of Inappropriate Sexual Behaviorsmentioning

confidence: 99%