Sexually Transmitted Infections and Male Infertility: Old Enigma, New Insights

Kushwaha, Bhavana; Gupta, Gopal

doi:10.1007/978-981-10-4017-7_12

Cited by 7 publications

(3 citation statements)

References 169 publications

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“…However, treatment with either the probiotic strain 505 or its synbiotics with CT, especially the synbiotics, prevent the UCMS-induced changes in the expressions of these genes which may lead to protection of testicular involution. In addition, the results for the preventive effects of 505 and synbiotics on steroidogenesis were in agreement with a study conducted by Kushwaha and Gupta ( 30 ) which showed that chronic stress had a negative effect on the male reproductive system via the HPG axis, effected by endocrine activity and Lh secretion. Lh interacts with its receptor Lhr and this activation is critical for spermatogenesis while Egfr is the prototypical member of its family of membrane associated intrinsic tyrosine kinase receptors, which are required for optimal embryonic testes growth ( 31 ).…”

Section: Discussionsupporting

confidence: 91%

A Synbiotic Combination of Lactobacillus gasseri 505 and Cudrania tricuspidata Leaf Extract Prevents Stress-Induced Testicular Dysfunction in Mice

et al. 2022

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This study investigated the effects of a synbiotic combination (Syn) of Lactobacillus gasseri 505 (505) and Cudrania tricuspidata leaf extract (CT) on the hypothalamic-pituitary-gonadal axis in mice under chronic stress. Unpredictable chronic mild stress (UCMS) significantly increased the serum levels of corticosterone, however, treatment with Syn suppressed UCMS-induced increases. Histopathological analysis of the testes showed that these organs experienced some damage during UCMS, but this was repaired following treatment with Syn. Similarly, the transcription levels of gonadotropin-releasing hormone (GnRH), GnRH receptor, and gonadotropins, moreover, testicular development (i.e., Adam5, Adam29, and Spam1) - and steroidogenesis (i.e., Lhr, Egfr, and StAR) -related genes were significantly downregulated by UCMS. These UCMS-induced changes were inhibited by the administration of Syn, which was confirmed by the results of in situ hybridization analysis. These results suggest that the administration of Syn could attenuate the testicular dysfunctions induced by UCMS.

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Section: Discussionsupporting

confidence: 91%

A Synbiotic Combination of Lactobacillus gasseri 505 and Cudrania tricuspidata Leaf Extract Prevents Stress-Induced Testicular Dysfunction in Mice

et al. 2022

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“…Antibacterial agents obliterate bacteria or subdue their growth or to stop the faster reproducing properties. The worldwide problem of antibiotic resistance is becoming one of the foremost scientific issues of current times [ 81 ]. The progress of new antibiotics is slow and complex process.…”

Section: General Pharmacology Of Rumex Dentatusmentioning

confidence: 99%

Critical review on Rumex dentatus L. a strong pharmacophore and the future medicine: Pharmacology, phytochemical analysis and traditional uses

Khaliq¹,

Akhter²,

Sultan³

et al. 2023

Heliyon

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“…Since these diseases do not cause immunity, it is possible for each person to be infected several times during lifetime [4]. Risk factors include having multiple sexual partners, starting sexual activity at early age, poverty, smoking, low awareness, low literacy, depression, risky sexual behavior, and history of other sexually transmitted diseases [5].…”

Section: Introductionmentioning

confidence: 99%

Effect of educational program based on planned behavior theory on preventive behaviors of sexually transmitted diseases of married women

Shamsolahi¹,

Mirmolaei²,

Kasaeian³

et al. 2021

HIV & AIDS Review

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Introduction: Sexually transmitted diseases (STDs) are among the most common infectious diseases in women. The aim of the present study was to determine the effect of teaching based on theory of planned behavior on preventive behaviors of STDs of married women. Material and methods:Study subjects consisted of 114 women who attended a university-affiliated hospital in Tehran, Iran. They were randomly assigned into intervention group (n = 58) and control group (n = 56). Women in intervention group participated in a four-session educational program based on a theory of planned behavior. Women in control group received a routine education. Data-gathering tool was a researcher-made questionnaire, including demographic characteristics, knowledge on sexually transmitted diseases, attitude, subjective norms, perceived behavioral control, and intention for healthy behavior along with self-reported sexual behaviors. Data was analyzed using repeated measure ANOVA.Results: All constructs of the theory of planned behavior along with the knowledge and reported sexual behaviors improved significantly in intervention group in comparison to controls. The theory of planned behavior was effective in the increase of knowledge and improvement of attitude, subjective norms, perceived behavioral control, and intention for healthy behaviors in married women. It was also effective in improving healthier sexual behaviors.Conclusions: Education program based on the theory of planned behavior was effective on preventive behaviors of STDs of married women. We recommend using this theory in prevention programs for sexually transmitted diseases in married women.

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Sexually Transmitted Infections and Male Infertility: Old Enigma, New Insights

Cited by 7 publications

References 169 publications

A Synbiotic Combination of Lactobacillus gasseri 505 and Cudrania tricuspidata Leaf Extract Prevents Stress-Induced Testicular Dysfunction in Mice

A Synbiotic Combination of Lactobacillus gasseri 505 and Cudrania tricuspidata Leaf Extract Prevents Stress-Induced Testicular Dysfunction in Mice

Critical review on Rumex dentatus L. a strong pharmacophore and the future medicine: Pharmacology, phytochemical analysis and traditional uses

Effect of educational program based on planned behavior theory on preventive behaviors of sexually transmitted diseases of married women

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