Shape‐Changing DNA‐Linked Nanoparticle Films Dictated by Lateral and Vertical Patterns

Kim, Jong-Wook; Lee, Sung‐Hee; Choi, Jisu; Baek, Kyungnae; Shim, Tae Soup; Hyun, Jerome K.; Park, So‐Jung

doi:10.1002/adma.202109091

Cited by 11 publications

(14 citation statements)

References 52 publications

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“…The NP film was made up of stacks of domains, each composed of particles with different plasmonic properties and grafted with a different combination of DNA sequences. Compared with the traditional lithography technique of sequential etching, this strategy can control the laser to change the selective removal of target regions in the film, so that the selected DNA sequence carrying information can shrink and expand in a programmable way, resulting in highly oriented structural deformation [ 64 ]. In another case, Mitta et al prepared AuNPs by drop-casting and embedded them into DNA films to obtain composite films with high stability and enhanced response to UV light, indicating that 2D DNA films can be used as carriers for the modification and functionalization of biomimetic nanomaterials [ 65 ].…”

Section: Biomolecular Functional Nanomaterialsmentioning

confidence: 99%

Biomolecule-mimetic nanomaterials for photothermal and photodynamic therapy of cancers: Bridging nanobiotechnology and biomedicine

Yang

Zhu

et al. 2022

J Nanobiotechnol

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Nanomaterial-based phototherapy has become an important research direction for cancer therapy, but it still to face some obstacles, such as the toxic side effects and low target specificity. The biomimetic synthesis of nanomaterials using biomolecules is a potential strategy to improve photothermal therapy (PTT) and photodynamic therapy (PDT) techniques due to their endowed biocompatibility, degradability, low toxicity, and specific targeting. This review presents recent advances in the biomolecule-mimetic synthesis of functional nanomaterials for PTT and PDT of cancers. First, we introduce four biomimetic synthesis methods via some case studies and discuss the advantages of each method. Then, we introduce the synthesis of nanomaterials using some biomolecules such as DNA, RNA, protein, peptide, polydopamine, and others, and discuss in detail how to regulate the structure and functions of the obtained biomimetic nanomaterials. Finally, potential applications of biomimetic nanomaterials for both PTT and PDT of cancers are demonstrated and discussed. We believe that this work is valuable for readers to understand the mechanisms of biomimetic synthesis and nanomaterial-based phototherapy techniques, and will contribute to bridging nanotechnology and biomedicine to realize novel highly effective cancer therapies.

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Section: Biomolecular Functional Nanomaterialsmentioning

confidence: 99%

Biomolecule-mimetic nanomaterials for photothermal and photodynamic therapy of cancers: Bridging nanobiotechnology and biomedicine

Yang

Zhu

et al. 2022

J Nanobiotechnol

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“…Shape change of ultrathin films can be directed using DNA signals (25)(26)(27). DNA sequences can also swell or shrink hydrogels (17,18,(28)(29)(30)(31), but afterward, these hydrogels are no longer responsive to DNA instructions.…”

Section: Main Textmentioning

confidence: 99%

Shape-shifting microgel automata controlled by DNA sequence instructions

Shi

Chen

Fern

et al. 2022

Preprint

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Controlling material shapes using information-bearing molecular signals is central to the creation of autonomous, reconfigurable soft devices. While physical and chemical stimuli can direct simple material swelling, bending, or folding, it has been challenging to direct multi-step shape-change programs crucial for complex, robotic tasks. Here, we demonstrate gel automata—sub-millimeter, photopatterned, highly swellable DNA gels—whose parts grow or shrink in response to easily designed DNA activator sequences, allowing for precisely controlled device articulation. We design and fabricate gel automata that reversibly transform between different letter shapes, and use neural networks to design automata that transform into every even or every odd numeral via designed reconfiguration programs. This sequential and repetitive metamorphosis of materials via chemical reorganization could dramatically advance our ability to manipulate micro-particles, cells, and tissues.

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“…[52] The planetary nano-gearsets are formed by connecting two DNA origami rings and cross-linking two Au nanoparticles in between. Kim et al demonstrated that photopatterning of DNAdirected Au nanorod self-assembled films is possible by the photothermal effect when illuminated by a laser [53] . As the illuminated spots heat up due to the photothermal effect, the disentanglement of the nanoparticles from the DNA linkage is possible by the application of a laser of sufficient intensity and suitable wavelength, Figure 4 (c).…”

Section: 13mentioning

confidence: 99%

Section: 13mentioning

confidence: 99%

A Review on Self-Assembled Colloidal Nanoparticle Clusters, Patterns and Films: Emerging Synthesis Techniques and Applications

Borah

Minja

et al. 2022

Preprint

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The colloidal synthesis of functional nanoparticles have gained tremendous scientific attention in the last decades. In parallel to these advancements, another rapidly growing area is the self-assembly of these colloidal nanoparticles into greater periodic arrangements. Firstly, the organization of nanoparticles into ordered structures is important for obtaining functional interfaces that extend or even amplify the intrinsic properties of the constituting nanoparticles at a larger scale. The synthesis of large-scale interfaces using complex or intricately designed nanostructures as building blocks, requires highly controllable self-assembly techniques down to the nanoscale. In certain cases, for example, when dealing with plasmonic nanoparticles, the assembly of the nanoparticles further enhances their properties by coupling phenomena. In other cases, the process of self-assembly itself is useful in the final application such as in sensing and drug delivery, amongst others. In view of the growing importance of this field, this review provides a comprehensive overview of the recent developments in the field of self-assembly of different nanostructures and their applications. For clarity, the self-assembled nanostructures are classified into two broad categories: finite clusters/patterns, and infinite films. Different state-of-the-art techniques to obtain these nanostructures are discussed in detail, before discussing the applications where the self-assembly significantly enhances the performance of the process.

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Shape‐Changing DNA‐Linked Nanoparticle Films Dictated by Lateral and Vertical Patterns

Cited by 11 publications

References 52 publications

Biomolecule-mimetic nanomaterials for photothermal and photodynamic therapy of cancers: Bridging nanobiotechnology and biomedicine

Biomolecule-mimetic nanomaterials for photothermal and photodynamic therapy of cancers: Bridging nanobiotechnology and biomedicine

Shape-shifting microgel automata controlled by DNA sequence instructions

A Review on Self-Assembled Colloidal Nanoparticle Clusters, Patterns and Films: Emerging Synthesis Techniques and Applications

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