Shape optimization of a centrifugal blood pump by coupling CFD with metamodel-assisted genetic algorithm

Ghadimi, Behnam; Nejat, Amir; Nourbakhsh, S. Ahmad; Naderi, Nasim

doi:10.1007/s10047-018-1072-z

Cited by 29 publications

(28 citation statements)

References 13 publications

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“…An impeller with a superior hydrodynamic efficiency is expected to minimize hemolysis . In this study, the highest hydrodynamically efficient impeller was chosen to be optimum.…”

Section: Discussionmentioning

confidence: 99%

“…An impeller with a superior hydrodynamic efficiency is expected to minimize hemolysis. 19 In this study, the highest hydrodynamically efficient impeller was chosen to be optimum. However, impeller and guide vane improvement, including a detailed design, is required for further reduction of hemolysis and thrombus formation by hemolysis tests and a CFD analysis.…”

Section: Discussionmentioning

confidence: 99%

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Development of rear‐impeller axial flow blood pump for realization of axial flow blood pump installed at aortic valve position

et al. 2019

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In this study, rear‐impeller axial flow blood pumps (RIAFBP) were developed to realize a trans‐valve axial ventricular assist device (VAD) which consists of the latter blood pump and a polymer monomembrane aortic valve, such as the jellyfish valve. The motor of the RIAFBP is installed in the left ventricle, and its impeller is placed at the aortic valve position. In the prototype RIAFBP, the rotation of the motor is sustained by polyethylene bushings. The RIAFBP has a length of 50 mm and diameter of 19.6 mm. The miniature RIAFBP has the same construction as that of the prototype; however, it employs a ceramic bearing and fin bearing to improve endurance and to reduce blood stagnation. The miniature RIAFBP has a length of 63 mm and diameter of 12 mm. Both RIAFBPs were examined by an in vitro experiment using a 33% glycerin solution. The prototype RIAFBP achieved a maximum pump outflow of 8.5 L/min against a pump head of 100 mm Hg at a rotational speed of 12 000 rpm. The miniature RIAFBP achieved 7 L/min against a pump head of 70 mm Hg at a rotational speed of 21 600 rpm. In conclusion, the miniature RIAFBP has enough pump performance to realize the trans‐valve axial VAD.

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“…An impeller with a superior hydrodynamic efficiency is expected to minimize hemolysis . In this study, the highest hydrodynamically efficient impeller was chosen to be optimum.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Development of rear‐impeller axial flow blood pump for realization of axial flow blood pump installed at aortic valve position

et al. 2019

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“…2 A computational fluid dynamics (CFD) technique is used to resolve the discrete distribution of the flow field of blood flow over a continuous area, thereby approximately simulating blood flow and numerically simulating the differential equation for controlling fluid flow in a blood pump by computer numerical simulation. Ghadimi et al 3 optimized the impeller and volute geometry of a typical centrifugal blood pump and used efficiency instead of hemolysis index as an objective function by coupling CFD with metamodel-assisted genetic algorithm. Ozturk et al 4 enhanced the hydrodynamic and hemolytic performance with a blade curvature compared to the straight-blade configuration of the blood pump by CFD.…”

Section: Introductionmentioning

confidence: 99%

Analysis of flow field and hemolysis index in axial flow blood pump by computational fluid dynamics–discrete element method

et al. 2020

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To fully study the relationship between the internal flow field and hemolysis index in an axial flow blood pump, a computational fluid dynamics–discrete element method coupled calculation method was used. Through numerical analysis under conditions of 6000, 8000, and 10,000 r/min, it was found that there was flow separation of blood cell particles in the tip of the impeller and the guide vane behind the impeller. The flow field has a larger pressure gradient distribution, which reduces the lift ratio of the blood pump and easily causes blood cell damage. The study shows that the hemolysis index obtained by the computational fluid dynamics—discrete element method is 4.75% higher than that from the traditional computational fluid dynamics method, which indicates the impact of microcollision between erythrocyte particles and walls on hemolysis index and also further verifies the validity of the computational fluid dynamics–discrete element coupling method. Through the hydraulic and particle image velocimetry experiments of the blood pump, the coincidence between numerical calculation and experiment is analyzed from macro and micro aspects, which shows that the numerical calculation method is feasible.

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“…Many studies are focused on the design advancement of the blood pump, however, the influence of geometrical aspects of the blood pump like blade number, blade tip width, splitter blades, etc., on the hemodynamic characteristics are limited in the literature. The recent designs of blood pumps involve additional magnets to levitate the impeller, which considerably increases the weight and cost of the device.…”

Section: Introductionmentioning

confidence: 99%

Numerical simulation of centrifugal and hemodynamically levitated LVAD for performance improvement

Kannojiya

Das

2019

Artificial Organs

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Left ventricular assist device (LVAD) provides an effective artificial support system to the heart patients. Despite the improved life survival rate, complications like hemolysis, blood trauma, and thrombus formation still limit the performance of the blood pump. The geometrical aspects of blood pumps majorly influence the hemodynamics, therefore these devices must be carefully engineered. In this work, several versions of centrifugal blood pumps are simulated using ANSYS-CFX to propose a best compatible design for LVAD. A hemodynamic levitation approach for the impeller is also suggested to overcome the cost and weight issue associated with the magnetic levitation. The blood flow is modeled by implementing Bird-Carreau model and its turbulence is solved using the SST turbulence model. The influence of the blade profile, blade tip width, blade numbers, and splitter blades on the hemodynamic characteristics through the pump is observed. An optimum design of centrifugal blood pump for the assistance of failed ventricle is proposed that can effectively pump the blood from the left ventricle to the ascending aorta. The proposal can be adopted by LVAD designers to have hemodynamically tuned efficient product. K E Y W O R D Scentrifugal blood pump, damage index estimates, hemolysis, left ventricular assist device, non-Newtonian modeling E2 |

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Shape optimization of a centrifugal blood pump by coupling CFD with metamodel-assisted genetic algorithm

Cited by 29 publications

References 13 publications

Development of rear‐impeller axial flow blood pump for realization of axial flow blood pump installed at aortic valve position

Development of rear‐impeller axial flow blood pump for realization of axial flow blood pump installed at aortic valve position

Analysis of flow field and hemolysis index in axial flow blood pump by computational fluid dynamics–discrete element method

Numerical simulation of centrifugal and hemodynamically levitated LVAD for performance improvement

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