Short- and long-term biomechanical and morphological study of new suture types in abdominal wall closure

Simón-Allué, Raquel; Pérez-López, Paloma; Sotomayor, Sandra; Peña, Estefanía; Pascual, Gemma; Calvo, Begoña

doi:10.1016/j.jmbbm.2014.04.014

Cited by 14 publications

(12 citation statements)

References 24 publications

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“…Oni et al did not demonstrate a difference in tensile strength six weeks after fascial closure with bidirectional polydioxanone barbed suture and monofilament polydioxanone suture in a porcine model . Similarly, Simon‐Allue et al did not demonstrate a difference in stiffness or tensile load at failure in rabbit linea alba closed with monofilament polydioxanone and barbed polydioxanone . We did not demonstrate a difference in stiffness for the different sutures although the load at failure was significantly greater for polydioxanone than barbed GTC.…”

Section: Discussioncontrasting

confidence: 51%

“…The absence of a knot is proposed to decrease tissue reaction due to a reduced knot volume and barbed suture has been suggested as an alternative to conventional suture for all soft tissue closures where absorbable suture material is appropriate . Biomechanical studies comparing barbed and monofilament sutures in the dermis, gastro‐intestinal tract, urinary bladder, diaphragm, abdominal wall, and tendon are reported.…”

Section: Introductionmentioning

confidence: 99%

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Tensile Comparison of Polydioxanone, Polyglyconate, and Barbed Glycolide‐Trimethylene Carbonate Suture in Canine Cadaveric Tensor Fascia Lata

et al. 2016

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Section: Discussioncontrasting

confidence: 51%

Section: Introductionmentioning

confidence: 99%

Tensile Comparison of Polydioxanone, Polyglyconate, and Barbed Glycolide‐Trimethylene Carbonate Suture in Canine Cadaveric Tensor Fascia Lata

et al. 2016

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“…Absorbability is also a key consideration for barbed sutures. For abdominal wall closure, non-absorbable sutures appear to be the most appropriate, mimicking the mechanical forces of healthy tissue [16]. A recent systematic review and meta-analysis of barbed suture in laparoscopic surgery comprising 1991 gynecologic patients demonstrated a significantly shorter duration of suturing with barbed sutures (3.9-13 min) compared to smooth sutures (6.2-20.4 min) during hysterectomy.…”

Section: Discussionmentioning

confidence: 99%

Unidirectional barbed sutures as a novel technique for laparoscopic ventral hernia repair

et al. 2015

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The barbed suture closure system could be used for rapid and effective primary defect closure in laparoscopic ventral hernia repair in addition to intraperitoneal mesh placement. No significant difference in operating time was detected when compared to the mesh-only approach. Further evidence to support these findings and longer follow-up periods is warranted to evaluate short- and long-term complications.

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“…Additionally, various approaches have been made to optimize the surgical technique, for example for midline laparotomy closure [2,3,4]. Finally, the choice of the optimal suture material determining the foreign body reaction is at least as important but is still under discussion [5]. …”

Section: Introductionmentioning

confidence: 99%

Polyvinylidene Fluoride as a Suture Material: Evaluation of Comet Tail-Like Infiltrate and Foreign Body Granuloma

et al. 2015

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Background: Biocompatibility and tissue integration of a surgical suture are decisive factors for wound healing and therefore for the success of sutures. The optimal suture material is still under discussion. Polyvinylidene fluoride (PVDF) is described to have superior properties of biocompatibility and is therefore frequently used as a mesh component. Only little information is available about its use as a suture material. The aim of this study was to evaluate the biocompatibility of PVDF as a suture material in comparison to 5 different established sutures in a rat model. Methods: In 30 male rats, a monofilamental PVDF suture (Resopren®) and 5 established control suture materials [polyester (Miralene®), polytetrafluoroethylene (Gore®), poliglecaprone (Monocryl®), polydioxanone (Monoplus®), polyglactin 910 (Vicryl®), USP size 3-0] were placed in the subcutaneous layer of the abdominal wall without knot or tension. After 3, 7 or 21 days, the abdominal walls were explanted for histopathological and immunohistochemical investigation with special regard to the size and quality of foreign body granuloma and the length of the comet tail-like infiltrate (CTI). Results: The PVDF sutures showed the smallest size of foreign body granuloma (60 ± 14 µm) and the smallest CTI length (343 ± 60 µm) of all polymers after 21 days. Only PVDF (Resopren) and polydioxanone (Monoplus) showed a significant collagen I/III ratio increase between days 3 and 21 (p = 0.009 and p = 0.016). The quality of foreign body reaction regarding inflammation, proliferation and fibrotic remodeling was similar between all suture materials. Conclusions: Our data indicate that monofilamental PVDF sutures show a favorable foreign body reaction with small granuloma sizes and CTI length in comparison to established sutures. Its use as a suture material in general surgery could therefore be extended in the future. To reinforce these findings, further clinical studies need to be conducted.

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Short- and long-term biomechanical and morphological study of new suture types in abdominal wall closure

Cited by 14 publications

References 24 publications

Tensile Comparison of Polydioxanone, Polyglyconate, and Barbed Glycolide‐Trimethylene Carbonate Suture in Canine Cadaveric Tensor Fascia Lata

Tensile Comparison of Polydioxanone, Polyglyconate, and Barbed Glycolide‐Trimethylene Carbonate Suture in Canine Cadaveric Tensor Fascia Lata

Unidirectional barbed sutures as a novel technique for laparoscopic ventral hernia repair

Polyvinylidene Fluoride as a Suture Material: Evaluation of Comet Tail-Like Infiltrate and Foreign Body Granuloma

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