Short-duration exposure to 2.45 GHz microwave radiation induces DNA damage in Sprague Dawley rats reproductive systems

Abstract

The genotoxic effects of 2.45 GHz microwave (MW) radiation on the testis and ovary of Sprague Dawley rats was investigated. The animals were exposed to varying levels of specific absorption rate (SAR) of 0 (control), 0.48, 0.95, 1.43, 1.91, 2.39, 2.90, 3.40, 3.80 and 4.30 Wkg-1 , for 10 min. The induction of DNA damages was assessed using DNA direct amplification of length polymorphisms (DALP) and validated with single cell gel electrophoresis (SCGE) comet assay for same cells at SAR 2.39 Wkg-1. Potential damage at the organ level was assessed by histopathological study. The results show significant differences in the Olive moment and % DNA in the blood of the exposed animals when compared with the control (p < 0.05). Hyperchromasia was observed in the ovary of the animals exposed to MW radiation. Also, there was reduction in the number of germ cells and cell disorganization in the testis of exposed group with increasing SARs. These results suggest that MW radiation has the potential to affect both male and female fertility adversely.

Cancer risks from chest radiography of young adults: A pilot study at a health facility in South West Nigeria

“…Data on the risks of cancer induction from low dose ionizing radiation can be found in [10] , [11] , [12] , [13] , [14] . Beyond cancer induction other radiation risks have been reported [15] , [16] , [17] .…”

Cancer risks from head radiography procedures

“…Cancer induction in low dose radiation cannot be overruled. Even, microwave radiation is known to induce DNA damage, produce chromosomal aberration, histological changes, genotoxic effects and others in tissues of exposed rats [6][7][8][9]. It is based on this fact that this study was embarked upon in order to estimate the risks of cancer induction in head radiography with a view to promote dose optimization and enhance patient safety.…”