Short-Term Carbohydrate-Restricted Diet for Weight Loss in Severely Obese Women

Triffoni-Melo, Andresa de Toledo; Dick-de-Paula, Ingrid; Portari, Guilherme Vannucchi; Jordão, Alceu Afonso; Chiarello, Paula Garcia; Diez‐Garcia, Rosa Wanda

doi:10.1007/s11695-010-0110-6

Cited by 14 publications

(10 citation statements)

References 37 publications

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“…It is a retrospective cohort study with all the disadvantages of these studies. The untreated group defined by early‐onset of lack of tolerance of rimonabant provides a small self‐selected parallel comparison group but shows weight reductions similar to those seen in a randomised study of dietary therapy in a prebariatric population of 1.7 kg (5).…”

Section: Effects Of Long‐term Treatment With Rimonabant In Morbidly mentioning

confidence: 88%

“…Presurgical management of patients due to undergo bariatric surgery typically involves the prescription of a low calorie, low carbohydrate diet to reduce hepatomegaly and fatty liver. In prebariatric patients a trial of 19 patients showed an average 4.4 kg loss with this intervention as opposed to 2.6 kg with calorie restriction (5). In this audit rimonabant therapy resulted in a non‐significant 3% weight loss (4.6 ± 11 kg; 1.7 ± 4 kg/m 2 ) allied with predictable reductions in blood pressure, glucose; and HbA 1c , triglycerides and increased HDL‐C.…”

Section: Effects Of Long‐term Treatment With Rimonabant In Morbidly mentioning

confidence: 99%

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Rimonabant improves cholesterol, insulin resistance and markers of non-alcoholic fatty liver in morbidly obese patients: a retrospective cohort study

Wierzbicki

Pendleton

McMahon

et al. 2011

International Journal of Clinical Practice

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Section: Effects Of Long‐term Treatment With Rimonabant In Morbidly mentioning

confidence: 88%

Section: Effects Of Long‐term Treatment With Rimonabant In Morbidly mentioning

confidence: 99%

Rimonabant improves cholesterol, insulin resistance and markers of non-alcoholic fatty liver in morbidly obese patients: a retrospective cohort study

Wierzbicki

Pendleton

McMahon

et al. 2011

International Journal of Clinical Practice

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“…Moreover, our previous studies have reported that obesity is more prevalent among Asian Indian women as compared to men, specifically after child birth and in the postmenopausal phase [ 52 , 53 ]. Further, the trial duration of 8 weeks in the present study could be a possible limitation, but studies of 1 and 4 weeks duration have been published previously [ 12 , 54 ]. Studies of longer duration should be conducted to evaluate the long-term effect on kidney function, reproductive health, bone matrix and life span.…”

Section: Discussionmentioning

confidence: 98%

A randomized controlled trial to evaluate the effects of high P rotein C omplete (l A cto) VE geta R ian (PACER) diet in non-diabetic obese Asian Indians in North India

Bhardwaj

Misra

Gulati

et al. 2017

Heliyon

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In view of the increasing prevalence of obesity in largely vegetarian Asian Indians, it is important to research a high protein, low carbohydrate vegetarian diet. The present study was designed to evaluate the effects of a “High Protein Complete (lacto) VEgetaRian Diet (Acronym; ‘PACER diet’), on weight, body composition and metabolic profiles in non-diabetic obese Asian Indians living in north India.In this 8-week randomized control trial, 102 vegetarian subjects with body mass index (BMI) >25 kg/m2 were randomized to either a test diet (PACER diet; high protein, high fat and moderately low carbohydrate, lacto-vegetarian diet) or control diet (standard vegetarian diet formulated as the dietary guidelines for Asian Indians) after 4 weeks of diet and exercise run-in period. A standard exercise protocol was followed for both groups. Body weight, BMI, waist circumference (WC), blood pressure, fasting plasma glucose (FPG), fasting serum insulin and lipid profile were assessed before and after the intervention.There was significant weight loss along with improvements in cardio-metabolic risk factors among both the groups post intervention. Percent reductions in the intervention group for weight (6.1± 2.9; p < 0.001), WC (3.9 ± 1.7; p < 0.001), FPG (5.9 ± 3.2; p < 0.001), total cholesterol (10.2 ± 6.3: p < 0.001), serum triacylglycerol (13.6 ± 10.6; p < 0.001) and low-density lipoprotein cholesterol (11.9 ± 7.1; p < 0.001]) were significantly greater than the control diet group. In summary, intervention with a PACER diet (high protein, high fat and moderately low carbohydrate, lacto-vegetarian diet) showed significant improvement in weight loss, body composition and cardio-metabolic profile as compared to a standard vegetarian diet among obese Asian Indians in north India.

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“…This study was approved by the Research Ethics Committee of HCFMRP-USP (Protocol number 2937/2007) and it is a continuation of a greater study on severe obesity and low-carbohydrate diet 20 .…”

Section: E T H O D Smentioning

confidence: 99%

Effect of weight and body composition changes on waist measurement of severely obese women receiving carbohydrate-restricted diet

2014

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OBJECTIVE: To evaluate the effect of weight and body composition changes on waist measurement of severely obese women receiving a low-carbohydrate diet for a short-term. METHODS: Nineteen severely obese women divided into an intervention and a control group received a low-carbohydrate diet and a conventional diet, respectively, both with 1,200kcal, for seven days. Anthropometric measurements such as weight, body mass index, arm circumference, waist circumference (at the navel), two proposed measurements of waist circumference (waist circumference 1, 10cm above the navel; and waist circumference 2, 20cm above the navel), hip circumference; and body composition (lean mass and fat mass) were performed at baseline and end of the study. RESULTS: There was significant reduction of all variables in the intervention group (p<0.01), but the control group had no change in waist circumference (p=0.06) and hip circumference (p=0.36). Patients of the intervention group presented greater weight loss (4.4kg, p<0.01) and reduction of body mass index, waist circumference, waist circumference 1, waist circumference 2 (p<0.01), and fat mass (p=0.04) than the control group. CONCLUSION: The weight loss and body composition changes were greater in the low-carbohydrate group than in the conventional-diet group, and they had a greater impact on waist measurements. The proposed measurements (waist circumference 1 and waist circumference 2) were sensitive to weight reduction in both groups.

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Short-Term Carbohydrate-Restricted Diet for Weight Loss in Severely Obese Women

Abstract: Short-term RD was more efficient than CD regarding quick weight loss and waist circumference reduction, which may favor gastroplasty. Also, RD did not lead adverse metabolic effects.

Cited by 14 publications

References 37 publications

Rimonabant improves cholesterol, insulin resistance and markers of non-alcoholic fatty liver in morbidly obese patients: a retrospective cohort study

Rimonabant improves cholesterol, insulin resistance and markers of non-alcoholic fatty liver in morbidly obese patients: a retrospective cohort study

A randomized controlled trial to evaluate the effects of high P rotein C omplete (l A cto) VE geta R ian (PACER) diet in non-diabetic obese Asian Indians in North India

Effect of weight and body composition changes on waist measurement of severely obese women receiving carbohydrate-restricted diet

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