Short‐term clinical effects of commercially available gel containing Acacia arabica: a randomized controlled clinical trial

Abstract

Background: Certain plants used in folk medicine serve as a source of therapeutic agent by having antimicrobial and other multi-potential effects. This prospective, randomized, placebo and positively controlled clinical trial was designed to evaluate the short-term clinical effects of a commercially available gel containing Acacia arabica in the reduction of plaque and gingival inflammation in subjects with gingivitis. Methods: Ninety subjects diagnosed with chronic generalized gingivitis were selected and randomly divided into three groups: Group I -placebo gel, Group II -gumtone gel and Group III -1% chlorhexidine gel. Clinical evaluation was undertaken using the gingival index of Loe and Silness and the plaque index at baseline, 2 weeks, 4 weeks and 6 weeks. A subjective evaluation was undertaken by questionnaire. Results: Gumtone gel showed significant clinical improvement in gingival and plaque index scores as compared to a placebo gel. This improvement was comparable to 1% chlorhexidine gel. Unlike chlorhexidine gel, gumtone gel was not associated with any discolouration of teeth or unpleasant taste. Conclusions: Gumtone gel may be a useful herbal formulation for chemical plaque control agent and improvement in plaque and gingival status.

The efficacy of chlorhexidine dentifrice or gel on plaque, clinical parameters of gingival inflammation and tooth discoloration: a systematic review

“…Various other studies have allowed subjects to apply a pea‐sized amount of CHX gel on the teeth gums with the index finger and leaving it undisturbed for approximately 5 min before rinsing. This resulted in significant improvement (as evaluated in studies 6–24 weeks) over the placebo gel group on plaque scores and the gingival index . The outcome of these studies taken together with the result of this review indicates that CHX gel is not effective in combination with toothbrushing but is effective when applied with a finger to teeth and gums.…”

The Effects of Plant Extracts on Dental Plaque and Caries

“…Gumtone gel showed significant clinical improvement in gingival and plaque index scores as compared to a placebo gel. Gumtone gel was not associated with any discoloration of teeth or unpleasant taste (Pradeep et al 2010).…”

EVALUATION OF ANTIMICROBIAL POTENTIAL OF Acacia nilotica (KIKAR) AGAINST ORAL PATHOGENS ASSOCIATED WITH CARIES AND PERIODONTITIS

“…Phenolic products may be subdivided into three main groups: flavonoids, phenolic acids and tannins (Borges et al, 2013). Acacia species were responsible for inhibition of cariogenic and periodontal pathogens (Pradeep et al, 2010b;Almas, 2001). The present research was carried out to determine the antimicrobial potential of aqueous, methanol and acetone extract of A. nilotica against oral microorganisms associated with periodontal diseases and caries.…”