Short-term Neonatal Outcome in Low-Risk, Spontaneous, Singleton, Late Preterm Deliveries

Melamed, Nir; Klinger, G; Tenenbaum-Gavish, Kinneret; Herscovici, Tina; Linder, Nehama; Hod, Moshe; Yogev, Yariv

doi:10.1097/aog.0b013e3181af6931

Cited by 163 publications

(139 citation statements)

References 28 publications

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“…The rates of neonatal complications observed in twins born at 34, 35, and 36 weeks of gestation did not differ significantly (except for antibiotic therapy between 34 and 35 weeks). Melamed et al (2009) studied neonatal complications in singletons and revealed a continuous relationship between gestational age and newborns' morbidity between 32 and 36 weeks of gestation, without any threshold of gestational age. The neonatal morbidity rate decreased only after completed 37 weeks of gestation.…”

Section: Discussionmentioning

confidence: 99%

Late Prematurity in Twins: A Polish Multicenter Study

et al. 2014

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The study aimed at investigating the impact of late prematurity (LPT) on neonatal outcome in twins and neonatal morbidity and mortality within LPT with regard to the completed weeks of gestation. The study was conducted in six tertiary obstetric departments from different provinces of Poland (Warsaw, Lublin, Poznan, Wroclaw, Bytom). It included 465 twin deliveries in the above centers in 2012. A comparative analysis of maternal factors, the course of pregnancy and delivery and neonatal outcome between LPT (34 + 0-36 + 6 weeks of gestation) and term groups (completed 37 weeks) was performed. The neonatal outcome included short-term morbidities. The analysis of neonatal complication rates according to completed gestational weeks was carried out. Out of 465 twin deliveries 213 (44.8%) were LPT and 156 (33.55%) were term. There were no neonatal deaths among LPT and term twins. One-third of LPT newborns suffered from respiratory disorders or required antibiotics, 40% had jaundice requiring phototherapy, and 30% were admitted to NICU. The analysis of neonatal morbidity with regard to each gestational week at delivery showed that most analyzed complications occurred less frequently with the advancing gestational age, especially respiratory disorders and NICU admissions. The only two factors with significant influence on neonatal morbidity rate were neonatal birth weight (OR = 0.43, 95% CI = 0.2-0.9, p = .02) and gestational age at delivery (OR = 0.62, 95% CI = 0.5-0.8, p < .01). LPT have a higher risk of neonatal morbidity than term twins. Gestational age and neonatal birth weight seem to play a crucial role in neonatal outcome in twins.

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Section: Discussionmentioning

confidence: 99%

Late Prematurity in Twins: A Polish Multicenter Study

et al. 2014

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“…Morbidity and mortality in newborn babies is directly related to gestational age at delivery, 13,14 which is an important clinical message because the decision to deliver the fetus preterm is often taken without medical indication. By contrast with other studies, our fi ndings show that infants exposed to chemotherapy in utero had a lower birthweight at the same gestational age than did infants not exposed to chemotherapy, a fi nding that was not aff ected by the amount of chemotherapy given and one that we believe is clinically irrelevant (because such low birthweight would not aff ect an otherwise healthy baby).…”

Section: Discussionmentioning

confidence: 99%

First trimester placental growth factor and soluble fms-like tyrosine kinase 1 are significantly related to PAPP-A levels

Gruson

Yuemo

Classen

et al. 2012

Clinical Chemistry and Laboratory Medicine (CCLM)

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"First trimester placental growth factor and soluble fms-like tyrosine kinase 1 are significantly related to PAPP-A levels" Sibylle Loibl, Sileny N Han, Gunter von Minckwitz, Marijke Bontenbal, Alistair Ring, Jerzy Giermek, Tanja Fehm, Kristel Van Calsteren, Sabine C Linn, Bettina Schlehe, Mina Mhallem Gziri, Pieter J Westenend, Volkmar Müller, Liesbeth Heyns, Brigitte Rack, Ben Van Calster, Nadia Harbeck, Miriam Lenhard, Michael J Halaska, Manfred Kaufmann, Valentina Nekljudova, Frederic Amant SummaryBackground Little is known about the treatment of breast cancer during pregnancy. We aimed to determine whether treatment for breast cancer during pregnancy is safe for both mother and child.

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“…Yet, they are physiologically and metabolically immature (2,8,10). Consequently, they are at a higher risk for morbidity when compared with full-term infants (4,7,10,11), such as respiratory distress (8,(12)(13)(14), hyperbilirubinaemia (8,(15)(16)(17), temperature instability (8,18), feeding difficulties (8,19,20), hypoglycaemia (8,18) and need for NICU admission (7,8,21).…”

Section: Introductionmentioning

confidence: 99%

“…However, in recent years, some concern rose in the literature because of the longer hospital stay and the higher costs of the latter group. Simultaneously, an increase in the rate of late preterm deliveries was observed over the last two decades (3), another reason why attention focused on their short-term and long-term outcome (1,(4)(5)(6)(7)(8).…”

Section: Introductionmentioning

confidence: 99%

Neonatal morbidity in singleton late preterm infants compared with full-term infants

Bucher¹,

Leone²,

Mieth³

et al. 2011

Z Geburtshilfe Neonatol

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Aim: The aim of this study was to test the hypothesis that singleton late preterm infants (34 0/7 to 36 6/7 weeks of gestation) compared with full-term infants have a higher incidence of short-term morbidity and stay longer in hospital. Methods: In this retrospective, multicentre study, electronic data of children born at five hospitals in Switzerland were recorded. Short-term outcome of late preterm infants was compared with a control group of full-term infants (39 0/7 to 40 6/7 weeks of gestation). Multiple gestations, pregnancies complicated by foetal malformations, maternal consumption of illicit drugs and infants with incomplete documentation were excluded. The results were corrected for gender imbalance. Results: Data from 530 late preterm and 1686 full-term infants were analysed. Compared with full-term infants, late preterm infants had a significant higher morbidity: respiratory distress (34.7% vs. 4.6%), hyperbilirubinaemia (47.7% vs. 3.4%), hypoglycaemia (14.3% vs. 0.6%), hypothermia (2.5% vs. 0.6%) and duration of hospitalization (mean, 9.9 days vs. 5.2 days). The risk to develop at least one complication was 7.6 (95% CI: 6.2-9.6) times higher among late preterm infants (70.8%) than among fullterm infants (9.3%). Conclusion: Singleton late preterm infants show considerably higher rate of medical complications and prolonged hospital stay compared with matched full-term infants and therefore need more medical and financial resources. To test the hypothesis that singleton late preterm infants (34 0/7 to 36 6/7 weeks of gestation) compared with full-term infants have a higher incidence of short-term morbidity and stay longer in hospital. Methods:In this retrospective, multi-centre study electronic data of children born at five hospitals in Switzerland were recorded. Short-term outcome of late preterm infants were compared with a control group of full-term infants (39 0/7 to 40 6/7 weeks of gestation).Multiple gestations, pregnancies complicated by fetal malformations, maternal consumption of illicit drugs and infants with incomplete documentation were excluded. The results were corrected for gender imbalance.Results: Data from 530 late preterm and 1686 full-term infants were analysed. Compared with full-term infants, late preterm infants had a significant higher morbidity: respiratory distress (34.7% versus 4.6%), hyperbilirubinaemia (47.7% versus 3.4%), hypoglycaemia (14.3% versus 0.6%), hypothermia (2.5% versus 0.6%), duration of hospitalization (mean 9.9 days versus 5.2 days). The risk to develop at least one complication was 7.6 (95% CI: 6.2 -9.6) times higher among late preterm infants (70.8%) than full-term infants (9.3%). Conclusion:Singleton late preterm infants show considerably higher rate of medical complications and prolonged hospital stay compared with matched full-term infants and therefore need more medical and financial resources. 3 Key notesLate preterm singletons (34 0/7 to 36 6/7 gestational weeks) show significantly higher rate of medical complications and prolonged hospital ...

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Short-term Neonatal Outcome in Low-Risk, Spontaneous, Singleton, Late Preterm Deliveries

Abstract: II.

Cited by 163 publications

References 28 publications

Late Prematurity in Twins: A Polish Multicenter Study

Late Prematurity in Twins: A Polish Multicenter Study

First trimester placental growth factor and soluble fms-like tyrosine kinase 1 are significantly related to PAPP-A levels

Neonatal morbidity in singleton late preterm infants compared with full-term infants

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