Short-Term Outcomes After Myopericarditis Related to COVID-19 Vaccination

Pareek, Manan; Steele, Jeremy; Asnes, Jeremy D.; Baldassarre, Lauren A.; Casale, Linda R.; Desai, Nihar R.; Elder, Robert W.; Faherty, Erin; Ferguson, Ian T.; Fishman, Robert F.; Ghazizadeh, Zaniar; Glick, Laura; Hall, E. Kevin; Khera, Rohan; Kokkinidis, Damianos G.; Kwan, Jennifer M.; O’Marr, Jamieson; Schussheim, Adam E.; Tuohy, Edward; Wang, Yanting; Spatz, Erica S.; Jacoby, Daniel; Miller, Edward Jeremy

doi:10.1016/j.jcmg.2022.03.026

Cited by 2 publications

(2 citation statements)

References 2 publications

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“…Most of the patients presented preserved biventricular function with pericardial effusion in 16% of them. CMR demonstrated the presence of oedema on T2-weighted images and T2 mapping sequences 14,62,64 . Signs of oedema, late gadolinium enhancement and increased T1 mapping values were mostly observed in inferolateral and anterolateral segments 14,62,64 .…”

Section: Clinical Presentation and Imaging Findingsmentioning

confidence: 99%

Myocarditis and COVID-19 related issues

Ciabatti,

Zocchi,

Olivotto

et al. 2023

gcsp

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The recent COVID-19 (Coronavirus Disease 2019) pandemic by SARS-CoV2 infection has caused millions of deaths and hospitalizations across the globe. In the early pandemic phases, the infection had been initially considered a primary pulmonary disease. However, increasing evidence has demonstrated a wide range of possible cardiac involvement. Most of systemic and cardiac damage is likely sustained by a complex interplay between inflammatory, immune-related and thrombotic mechanisms. Biventricular failure and myocardial damage with elevation of cardiac biomarkers have been reported in COVID-19 patients, although histological demonstration of acute myocarditis has been rarely documented. Indeed while cardiac magnetic resonance findings include different patterns of myocardial involvement in terms of late gadolinium enhancement, histological data from necropsy and endomyocardial biopsy showed peculiar inflammatory patterns, mostly composed by macrophages. On the other hand COVID-19 vaccines based on mRN technology have been also associated with increased risk of myocarditis. COVID-19 and mRNA vaccine-related myocarditis present different clinical and imaging presentations and recent data suggest the presence of distinctive immunological mechanisms involved.

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Section: Clinical Presentation and Imaging Findingsmentioning

confidence: 99%

Myocarditis and COVID-19 related issues

Ciabatti,

Zocchi,

Olivotto

et al. 2023

gcsp

View full text Add to dashboard Cite

show abstract

“…The current series included 7 to 9 patients with baseline and follow-up cardiac magnetic resonance imaging (CMRI). 1,2 Questions on acute myocarditis following mRNA COVID-19 vaccination addressed by this study are the risk of adverse events after discharge and the extent of residual myocardial dysfunction and scar formation.…”

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confidence: 99%