Short-term prophylaxis with cefotaxime for prostatic surgery

European Collaborative Study of Antibiotic Prophylaxis for Transurethral Resection of the Prostate

“…We also measured a number of fac tors related to morbidity and the only definable costrelated morbidity factor is that men who received prophy laxis required significantly fewer other post-operative an tibiotics and therefore the cost of these has to be consid ered when decisions on antibiotic policy are made. Pre vious studies have demonstrated a reduction in post-oper ative hospital stay [17,18], however no such reduction was demonstrated in this study. One possible explanation is that hospitals in different countries have varying poli cies about length of stay which may be influenced by social as well as medical factors.…”

Prophylactic Chemotherapy with Fosfomycin Trometamol Salt during Transurethral Prostatic Surgery: A Controlled Multicenter Clinical Trial

“…Fur thermore, FT significantly lowered the incidence of pos itive bacteriuria (14.8%) when compared with AMX (24.6%) and CTX (25%). Moreover, this antibiotic Gram-negative rods were the most frequent isolates from postoperative urine cultures (93.2%), with a preva lence of E. coli, KES group and Pseudomonas spp., ac cording to other observations [3,4,9]. Many of the iso lates were resistant to the three chosen antibiotics.…”

“…The bacteriological evaluation of these urinary iso lates demonstrated a general prevalence of gram-nega tive rods (68.9%), mainly Escherichia coli (26.6%), KES group (24.4%) and Pseudomonas aeruginosa (11.2%). Gram-positive strains (primarily group A streptococci and enterococci) were in the minority (31.1 %) [3,4,9] in contrast with the microbial distribu tion observed by other authors [8,12,13,16] (ta ble III). The percentage of urinary infections was quite similar to that observed in the literature after different chemo prophylactic treatments [3,6,7,9,[11][12][13].…”

“…Gram-positive strains (primarily group A streptococci and enterococci) were in the minority (31.1 %) [3,4,9] in contrast with the microbial distribu tion observed by other authors [8,12,13,16] (ta ble III). The percentage of urinary infections was quite similar to that observed in the literature after different chemo prophylactic treatments [3,6,7,9,[11][12][13]. There were no significant differences in the incidence and severity of postoperative infections among treatment groups in rela tion to the chosen class of antibiotics, route of adminis tration and duration of therapy, except for patients treated with the beta-lactam plus aminoglycoside combi nation who did not develop positive urine cultures.…”

Long‐term Follow‐up after Transurethral Prostatic Resection With or Without a Short Peri‐operative Antibiotic Course

“…Although no fatal infectious episodes arose during the period of observation, there were two severe infectious complications following endoscopic procedures in patients without appropriate antibiotic cover. These events underline the value of an adequate course of antibiotics in conjunction with such urological procedures at least in bacteriuric patients undergoing TUR (Williams et al, 1980;Hargreave et al, 1982;Olsen et al, 1983;Grabe et al, 1984a) or other urolugiual instrumentation procedures (Korbel and Maher, 1976).…”