Should Catheter Ablation be the Preferred Therapy for Reducing ICD Shocks?

Kuck, Karl‐Heinz

doi:10.1161/circep.109.896571

Cited by 15 publications

(5 citation statements)

References 83 publications

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“…It should be strongly considered in patients with ischemic cardiomyopathy with an LVEF of <35% and NYHA functional class III HF who present with ≥1 ICD shocks. 160 There is nearly an 8-fold increase in mortality in patients with low LVEF presenting with ≥2 ICD shocks. 152 In clinical practice, catheter ablation for scar-induced VT is often a second line therapy and used as an adjunct to AAD therapy.…”

Section: Hypertrophic Cardiomyopathymentioning

confidence: 99%

Clinical Management and Prevention of Sudden Cardiac Death

Yousuf

Chrispin

Tomaselli

et al. 2015

Circulation Research

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Despite the revolutionary advancements in the past 3 decades in the treatment of ventricular tachyarrhythmias with device-based therapy, sudden cardiac death (SCD) remains an enormous public health burden. Survivors of SCD are generally at high risk for recurrent events. The clinical management of such patients requires a multidisciplinary approach from postresuscitative care to a thorough cardiovascular investigation in an attempt to identify the underlying substrate, with potential to eliminate or modify the triggers through catheter ablation and ultimately an implantable cardioverter-defibrillator (ICD) for prompt treatment of recurrences in those at risk. Early recognition of low left ventricular ejection fraction as a strong predictor of death and association of ventricular arrhythmias with sudden death led to significant investigation with antiarrhythmic drugs. The lack of efficacy and the proarrhythmic effects of drugs catalyzed the development and investigation of the ICD through several major clinical trials that proved the efficacy of ICD as a bedrock tool to detect and promptly treat life-threatening arrhythmias. The ICD therapy is routinely used for primary prevention of SCD in patients with cardiomyopathy and high risk inherited arrhythmic conditions and secondary prevention in survivors of sudden cardiac arrest. This compendium will review the clinical management of those surviving SCD and discuss landmark studies of antiarrhythmic drugs, ICD, and cardiac resynchronization therapy in the primary and secondary prevention of SCD.

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Section: Hypertrophic Cardiomyopathymentioning

confidence: 99%

Clinical Management and Prevention of Sudden Cardiac Death

Yousuf

Chrispin

Tomaselli

et al. 2015

Circulation Research

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“…In order to improve quality of life and reduce the VA episodes, catheter ablation has been considered as a valid treatment option in addition to medical treatment in this setting, although only a moderate long-term efficacy at follow-up has been reported (13,14). These procedures are very challenging due to technical aspects, hemodynamic intolerance, and the complex arrhythmia substrates (4,14).…”

mentioning

confidence: 99%

Endo-Epicardial Homogenization of the Scar Versus Limited Substrate Ablation for the Treatment of Electrical Storms in Patients With Ischemic Cardiomyopathy

Biase

Santangeli

Burkhardt

et al. 2012

Journal of the American College of Cardiology

384

261

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“…Thus, substrate mapping is often the only method to perform catheter ablation in patients with an ICD (Kuck, 2009). By selecting catheter ablation for an individual patient, risks and benefits that are determined by patient characteristics, as well www.intechopen.com as the availability of appropriate facilities with technical expertise should be considered.…”

Section: Electroanatomic Systems and Substrate Mappingmentioning

confidence: 99%