Should low birth-weight be considered a relevant risk factor for rise in pulse pressure among adult overweight-obese subjects?

Abstract

Low birth-weight (BW) is related to rise in blood pressure (BP) later in life. Aim of this study is investigating whether presence of overweight-obesity modifies this relationship, independently from any additional correlate of metabolic syndrome. We studied 535 (216 M/319 F) otherwise healthy overweight-obese people (body mass index≥25 kg/m 2

The FADOI (Federation of Associations of Hospital Doctors on Internal Medicine) position paper on cardiovascular prevention in the higher risk complex patients

“…To these pathological conditions we could add, in the presence of a physiological history of preterm birth with low weight (low birth weight -expression of a thrifty phenotype), 48 another often unrecognized CV risk factor in adulthood for obesity, metabolic syndrome, insulin resistance, type 2 diabetes, high blood pressure variability as well as, among the voluptuary habits, inclination to smoking, more appetite and alcohol attitude. [49][50][51] In the overall assessment of CV risk we have to consider the presence of previous atrial fibrillation, asymptomatic carotid disease, depression and/or cognitive dysfunction and/or vascular dementia, concealed kidney failure, 52,53 obstructive sleep apnea syndrome (OSAS), 54 erectile dysfunction 55 and previous hospitalization for pneumonia, 56 all of these as emerging factors for higher CV risk. Controversial, also with regard to the cost/benefit of laboratory assays, is the role of testosterone 57,58 and vitamin D deficiency.…”