Sialoblastoma- long-term follow-up and remission for a rare salivary malignancy

Abstract

Sialoblastoma is a rare salivary neoplasm which presents either congenitally or during early infancy. It was originally considered a benign neoplasm, however a number of reported cases have documented locoregional recurrence and distant metastases. Currently, there is no consensus on the appropriate treatment for this neoplasm. We report on long term follow-up of a patient with metastatic sialoblastoma, and a brief discussion of the possible treatment modalities currently being considered.

Sialoblastoma of the parotid gland in a 13‐year‐old girl with multiple recurrences and long‐term follow‐up

“…When our patient presented with vertigo during the follow‐up period, a CT was performed to exclude a temporal bone and semicircular canal infiltration. A preoperative staging should always be performed as there have been reports of lymph node or lung metastases …”

Sialoblastoma: A literature review from 1966-2011

“…In one case sex has not been mentioned. 31 tumour were related to parotid,[37891011121314151617181920212223242526272829] 11 submandibular,[121830313233343536] two cheek minor salivary gland,[537] one was in relation with eyelid minor salivary gland[38] and one presented as face and neck mass[39] [Tables 1 and 2]…”

“…[3416262829] Most of them recurred within 24 month. Four cases of lung metastasis with two cases have multiple lung metastasis and two cases of cervical lymph node metastasis have been reported.…”

“…Four cases of lung metastasis with two cases have multiple lung metastasis and two cases of cervical lymph node metastasis have been reported. [102729] In reported cases no case succumbed to death due to recurrence or metastasis [Tables 1 and 2]. …”

Congenital sialoblastoma of the accessory parotid gland

“…1 In 1966, 2 cases were reported and referred to as embryomas. 2 In 1988, the term sialoblastoma was coined by Taylor to describe these lesions because it conveyed the dysontogenetic character and the site of the tumour. 3 These tumours generally originate in the parotid gland but may arise in the submandibular or minor salivary gland.…”