Sialolipoma of the Floor of the Mouth: A Case Report

Abstract

Intra-oral lipoma is a well-known entity, but lipomatous tumors including salivary gland tissue containing clustered or peripherally located ducts and acinar cells are uncommon. They are a newly recognized entity of salivary gland lipoma, designated sialolipoma. We describe a case of sialolipoma arising in the floor of the mouth presenting with apparently normal salivary gland tissue, as demonstrated by both histologic and immunohistochemical findings, in a 67-year-old female. Complete surgical removal of the tumor with preservation of the sublingual gland was implemented after a careful examination confirming that the lesion did not originate from the sublingual gland.

Sialolipoma in Minor Salivary Gland: Case Report and Review of the Literature

“…Although no preference for an anatomic site has been described for sialolipomas the palate is the most common site with 6 (37.5%) cases reported [1,5,[8][9][10][11]. In contrast, the buccal mucosa is the site most commonly affected by oral lipomas, corresponding to 30.5-45.7% of cases [6][7][8].…”

“…Most patients have been treated by conservative surgical excision, and neither local recurrence nor malignant transformation has been reported [1,3,12]. This article reports a case of sialolipoma located in the palate of a 72-year-old woman and presents a literature review of minor salivary gland sialolipomas.…”

“…Lipomatous lesions in the context of salivary glands have attracted interest in recent years and include lesions, such as sialolipoma [1,2]. Lipomas in the oral cavity are uncommon with a reported incidence of only 1-4.4% of all benign oral lesions [3,4].…”

“…Lipomas in the oral cavity are uncommon with a reported incidence of only 1-4.4% of all benign oral lesions [3,4]. Lipomas can be found in any oral site, especially the buccal mucosa [5][6][7] and tongue [3] as well as the palate, lip, and salivary glands [1,[8][9][10][11]. According to Nagao et al [9], sialolipoma is a lipomatous proliferation containing acinar and ductal structures bounded by a very thin fibrous tissue.…”

“…A thorough review of the English literature revealed 34 cases of oral sialolipoma, including 15 within the minor salivary glands [1,5,[8][9][10][11][12][13]. Most patients have been treated by conservative surgical excision, and neither local recurrence nor malignant transformation has been reported [1,3,12].…”