Sialosis: 35 cases of persistent parotid swelling from two countries

Non-Periodontal Oral Manifestations of Diabetes: A Framework for Medical Care Providers

“…However, the pathophysiology of these conditions is different. 13,25 Xerostomia, or the sensation of dry mouth, is reported to occur in 40-80% of diabetic patients and is related to decreased salivary flow rates, particularly in unstimulated whole saliva (the combination of secretions from all the salivary glands in the mouth). 4,17,21 Flow rates have been reported to be significantly lower in patients with poorly controlled diabetes 4,16,17 compared to patients whose diabetes is controlled or nondiabetic patients.…”

Sialosis: Cytomorphological significance in the diagnosis of an uncommon entity

“…[1] It mainly occurs in the parotid gland. [2] It is often bilateral and recurrent. But few cases with unilateral sialadenosis were reported as well.…”

Sonographic and CT Findings of Sialadenosis in a Child with Leukemia

“…This alteration at the micro-histological level allows acinar cells to expand as secretary granules accumulate in the cells, which leads to the gross change of diffuse enlargement of the salivary gland. The functionally deficient myoepithelial cells in sialadenosis may result from an autonomic neuropathy secondary to severe and long-standing metabolic or hormonal disorders such as diabetes mellitus, alcoholism (particularly with liver disease), liver cirrhosis, chronic malnutrition, and medications (1-4). Almost all cases with sialadenosis have been reported in adult patients.…”

“…Sialadenosis or sialosis is an uncommon disease of the salivary glands, characterized by asymptomatic, bilateral, diffuse swelling of the major salivary glands, particularly the parotid gland (1, 2). This condition usually does not affect salivary gland function.…”

“…This condition usually does not affect salivary gland function. Since systemic diseases or conditions such as diabetes mellitus and alcoholism related to the development of sialadenosis are rare in children (1), almost all cases with sialadenosis have been reported in adults. Aside from the rare incidence of this disease, the imaging findings of sialadenosis are even further seldom described.…”