SiC for Biomedical Applications

Saddow, Stephen E.; Frewin, Christopher L.; Cespedes, Fabiola Araujo; Gazziro, Mário; Bernadin, Evans; Thomas, Sylvia

doi:10.4028/www.scientific.net/msf.858.1010

Cited by 10 publications

(7 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Planar multisite electrodes (Chan et al, 2009 ; Lee et al, 2009 ; Suyatin et al, 2013 ; Saddow et al, 2016 )…”

Section: Discussionmentioning

confidence: 99%

“…The use of borosilicate glass as a structural substrate for implantable probes isolation is believed to be beneficial in improving isolation capabilities thus decreasing possible losses and crosstalk (Figure 6E ) (Lee et al, 2009 ; Lin et al, 2009 ). Other neural probe substrate materials include CVD–silicon carbide, gallium phosphide, as well as diamond and alumina ceramic substrates (Figure 6 ) (Moxon et al, 2004 ; Chan et al, 2009 ; Suyatin et al, 2013 ; Saddow et al, 2016 ). Electrical insulation is typically provided by multilayers of silicon oxide and silicon nitride and often extra-protected by Parylene-C, Liquid Crystal Polymer (LCP), or polyimide polymer coatings.…”

Section: Micromachined Microelectrodesmentioning

confidence: 99%

See 1 more Smart Citation

Neural Interfaces for Intracortical Recording: Requirements, Fabrication Methods, and Characteristics

2017

View full text Add to dashboard Cite

Implantable neural interfaces for central nervous system research have been designed with wire, polymer, or micromachining technologies over the past 70 years. Research on biocompatible materials, ideal probe shapes, and insertion methods has resulted in building more and more capable neural interfaces. Although the trend is promising, the long-term reliability of such devices has not yet met the required criteria for chronic human application. The performance of neural interfaces in chronic settings often degrades due to foreign body response to the implant that is initiated by the surgical procedure, and related to the probe structure, and material properties used in fabricating the neural interface. In this review, we identify the key requirements for neural interfaces for intracortical recording, describe the three different types of probes—microwire, micromachined, and polymer-based probes; their materials, fabrication methods, and discuss their characteristics and related challenges.

show abstract

“…Planar multisite electrodes (Chan et al, 2009 ; Lee et al, 2009 ; Suyatin et al, 2013 ; Saddow et al, 2016 )…”

Section: Discussionmentioning

confidence: 99%

Section: Micromachined Microelectrodesmentioning

confidence: 99%

Neural Interfaces for Intracortical Recording: Requirements, Fabrication Methods, and Characteristics

2017

View full text Add to dashboard Cite

show abstract

“…The main goal of this research is to build a test framework, by combining the RAA test method and a Weibull probability model to evaluate the risk and progression of device failure. In the future, we will apply this framework to evaluate other organic and inorganic materials that are widely used in biomedical device packaging, such as polyimide [ 31 , 32 , 33 , 34 , 35 , 36 ], SiC [ 37 , 38 ], diamond-like carbon [ 39 , 40 ], etc.…”

Section: Introductionmentioning

confidence: 99%

Stability Performance Analysis of Various Packaging Materials and Coating Strategies for Chronic Neural Implants under Accelerated, Reactive Aging Tests

et al. 2020

View full text Add to dashboard Cite

Reliable packaging for implantable neural prosthetic devices in body fluids is a long-standing challenge for devices’ chronic applications. This work studied the stability of Parylene C (PA), SiO2, and Si3N4 packages and coating strategies on tungsten wires using accelerated, reactive aging tests in three solutions: pH 7.4 phosphate-buffered saline (PBS), PBS + 30 mM H2O2, and PBS + 150 mM H2O2. Different combinations of coating thicknesses and deposition methods were studied at various testing temperatures. Analysis of the preliminary data shows that the pinholes/defects, cracks, and interface delamination are the main attributes of metal erosion and degradation in reactive aging solutions. Failure at the interface of package and metal is the dominating factor in the wire samples with open tips.

show abstract

“…Radiation hardness and chemical inertness makes SiC promising for sensing and detectors [4,5,6]. Due to the facts of its biocompatibility, SiC is used for various biomedical applications such as coatings and sensors [7,8]. In recent years, SiC is also gaining increasing interest as material for quantum applications.…”

Section: Introductionmentioning

confidence: 99%

Annealing-Induced Changes in the Nature of Point Defects in Sublimation-Grown Cubic Silicon Carbide

2019

View full text Add to dashboard Cite

In recent years, cubic silicon carbide (3C-SiC) has gained increasing interest as semiconductor material for energy saving and optoelectronic applications, such as intermediate-band solar cells, photoelectrochemical water splitting, and quantum key distribution, just to name a few. All these applications critically depend on further understanding of defect behavior at the atomic level and the possibility to actively control distinct defects. In this work, dopants as well as intrinsic defects were introduced into the 3C-SiC material in situ during sublimation growth. A series of isochronal temperature treatments were performed in order to investigate the temperature-dependent annealing behavior of point defects. The material was analyzed by temperature-dependent photoluminescence (PL) measurements. In our study, we found a variation in the overall PL intensity which can be considered as an indication of annealing-induced changes in structure, composition or concentration of point defects. Moreover, a number of dopant-related as well as intrinsic defects were identified. Among these defects, there were strong indications for the presence of the negatively charged nitrogen vacancy complex (NC–VSi)−, which is considered a promising candidate for spin qubits.

show abstract

SiC for Biomedical Applications

Cited by 10 publications

References 10 publications

Neural Interfaces for Intracortical Recording: Requirements, Fabrication Methods, and Characteristics

Neural Interfaces for Intracortical Recording: Requirements, Fabrication Methods, and Characteristics

Stability Performance Analysis of Various Packaging Materials and Coating Strategies for Chronic Neural Implants under Accelerated, Reactive Aging Tests

Annealing-Induced Changes in the Nature of Point Defects in Sublimation-Grown Cubic Silicon Carbide

Contact Info

Product

Resources

About