Sıçanlarda Oral Yüksek Doz Vitamin C Takviyesinin, Serum Vitamin C, Leptin ve Kortizol Parametrelerine Etkisi

Abstract

The aim of this study was to determine the changes in the blood levels of vitamin C, cortisol, and leptin, depending on the vitamin C supplementation administered orally at high dose intervals in rats. A total of 21 female Wistar Albino rats aged 6-9 months were randomly divided into three groups, each group containing seven animals. The first group is the control group, and the experiment groups are Vitamin C (1000 mg/kg CA group, orally), Vitamin C (3000 mg/kg CA group, orally). At the end of the total experiment period of 10 days, blood samples were taken into the serum tube as intracardiac. Vitamin C, cortisol, and leptin levels were determined from serum. It was found that there was no difference between the groups in serum vitamin C, cortisol, and leptin levels in blood samples. As a result, it has been observed that high-dose vitamin C supplements administered orally are not an effective way to increase the vitamin C pool in the body.