Signal Separation for Transabdominal Non-invasive Fetal Pulse Oximetry using Comb Filters

Böttrich, Marcel; Husar, Peter

doi:10.1109/embc.2018.8513614

Cited by 4 publications

(4 citation statements)

References 12 publications

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“…This work demonstrates an extended signal processing strategy for the extraction of the fetal pulse wave from mixed signals measured with transabdominal fetal pulse oximetry. The core of the strategy is an ANC and a comb filter, realized with algorithms presented in our former works [8], [7]. The application of a synchronous averaging procedure enhances the strategy to get a reliable information about the shape of the fetal pulse wave.…”

Section: Discussionmentioning

confidence: 99%

“…It can be seen that the signals in Setup 1 are disturbed by cross terms, represented by small peaks between the fetal and maternal component. They are analyzed more in detail in our former works in [10], [8]. Due to the heart rate variability, the maternal and fetal component are not separable in the overall frequency spectrum of the artificial signal (upper left plot of Fig.…”

Section: B Synthetic Datasetsmentioning

confidence: 99%

“…The measured signal consists of a mixture of the maternal and fetal pulse curves [4], [5], [10], [6]. One major challenge of the method is the extraction of the fetal pulse curve [5], [10], [8]. Following the principle of pulse oximetry, the resulting fetal PPG needs to be of high quality to clearly identify the signal level during systole and diastole of the fetus to conclude about the oxygen saturation.…”

Section: Introductionmentioning

confidence: 99%

“…Following the principle of pulse oximetry, the resulting fetal PPG needs to be of high quality to clearly identify the signal level during systole and diastole of the fetus to conclude about the oxygen saturation. Our previous work focused on the estimation of the fetal heart rate in time and frequency domain by using adaptive noise canceller and comb filters [8], [7]. We were able to extract the synthetically generated fetal signals and to identify single pulses in time domain.…”

Section: Introductionmentioning

confidence: 99%

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Estimating the Shape of the Fetal Pulse Curve for Transabdominal Pulse Oximetry using Synchronous Averaging

Böttrich

Laqua

Husar

2020

2020 42nd Annual International Conference of the IEEE Engineering in Medicine &Amp; Biology Society (EMBC)

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A sufficient oxygen supply of the fetus is necessary for a proper development of the organs. Transabdominal fetal pulse oximetry is a method that allows to measure the oxygenation of the fetal blood non-invasively by placing the light sources and photodetectors on the belly of the pregnant woman. The shape of the measured fetal pulse wave is needed to extract parameters for the estimation of the oxygen saturation. This work presents an extension of our previously presented signal processing strategy that allows to extract an average shape of the fetal pulse wave from noisy mixed photoplethysmograms (PPG) with dominating maternal and very weak fetal signal components. An adaptive noise canceller and a comb filter are used to suppress the maternal component. The quality of the resulting fetal signal is sufficient to identify single pulse waves in time domain. Further processing demonstrates the extraction of the mean shape of a single fetal pulse wave by synchronous averaging of several detected pulses. The method is evaluated with different datasets of several simulated and synthetic signals measured with a tissue mimicking phantom. The feasibility of the approach is demonstrated by preparing the mixed PPGs to perform fetal pulse oximetry in future studies. However, clinical measurements are needed to finally evaluate the proposed system beyond synthetic datasets.

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Section: Discussionmentioning

confidence: 99%

Section: B Synthetic Datasetsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Estimating the Shape of the Fetal Pulse Curve for Transabdominal Pulse Oximetry using Synchronous Averaging

Böttrich

Laqua

Husar

2020

2020 42nd Annual International Conference of the IEEE Engineering in Medicine &Amp; Biology Society (EMBC)

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Review of optical methods for fetal monitoring in utero

Gunther

Jayet

Sekar

et al. 2022

Journal of Biophotonics

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The current technology for monitoring fetal wellbeing during child birth is cardiotocography. However, CTG has high false positive rates that lead to unnecessary emergency Cesarean deliveries and false negatives that result in birth injuries. To curtail these issues, fetal pulse oximetery has been a topic of interest for many decades. Fetal pulse oximetry would yield the oxygen saturation of the fetus in utero and provide a more robust marker for clinicians to make decisions about performing emergency Cesarean deliveries. Here, we present a review of biomedical optical developments related to transabdominal fetal pulse oximetery in the biophotonics field and the challenges that must be overcome to make transabdominal pulse oximetry a clinical reality.

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