Spatially uniform cross-correlated sine-Wiener (CCSW) noises are imposed on each Hodgkin-Huxley (HH) neuron in a twodimensional (2D) regular network. Noise-induced spiral wave destruction and order-disorder spatial pattern transition can be observed by adjusting cross-correlation time or cross-correlation intensity of CCSW noises. The sudden change of the curve of synchronization factor and the time series of average membrane voltage F can be used to semiquantitatively assess this spatial pattern transition and spiral wave destruction induced by CCSW noises, respectively. In addition, moderate cross-correlation time and strong cross-correlation intensity of CCSW noises are both detrimental to survival of spiral wave. Comparing with non-crosscorrelated sine-Wiener noises, CCSW noises can destroy organized spiral wave with lesser noise amplitude.