The thermal transmission outcomes of Williamson Sutterby nanofluids owing to spinning cone with gyrotactic micro-organisms such as self-motivated microbes along with anisotropic slip conditions are probed in this article. The axisymmetric, unstable three-dimensional stream of fluids is swayed by magnetic and buoyancy forces. Utilizing appropriate similarity variables, the leading partial differential formulation for velocity, temperature, concentration, and motile density of nanofluids are altered into nonlinear ordinary differential equations and these equations together with boundary constraints are resolved by computational code for Runga-Kutta method in MATLAB platform. A concise computational strategy is made by altering the inputs of influential factors. Nusselt number, Sherwood number, and motile density number are also computed and listed in tables. As the magnitudes of the slip parameters expand, the Nusselt number, and Sherwood number decline. The velocity along the x-axis and the Nomenclature: Latin symbols: