Significance of gingers (Zingiberaceae) in Indian System of Medicine - Ayurveda: An overview

Kumar, K. M. Prabhu; Asish, G. R.; Sabu­, M.; Balachandran, Indira

doi:10.4103/0257-7941.131989

Cited by 65 publications

(41 citation statements)

References 23 publications

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“…Ethnobotany study about medicinal plants in the Buyan-Tamblingan Lake area, Bedugul, Bali revealed that Zingiberaceae was the largest family used by the local people as a traditional medicine, among other as antitoxin of scorpion, treatment for body warmer, anti-inflammatory, rheumatism, skin diseases, fever, weak heart, and painkiller [3]. In Ayurveda (a system of traditional medicine with historical roots in India), ginger was used for many kinds of treatment, as anti-inflammatory decoctions, a cardiac stimulant carminative, rheumatoid arthritis, inflammations, stomatopathy, pharyngopathy, cough, asthma, hiccough, dyspepsia, stomachalgia, obesity, diabetes, cephalalgia, tubercular glands and intermittent fevers [4].…”

Section: Introductionmentioning

confidence: 99%

Distribution and Phytocomponent in the Ethanol Extract of Globba candida Gagnep. (Zingiberaceae) by GC-MS Analysis

Andila

Tirta²

2019

JTLS

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Globba is the third largest genera in the Zingiberaceae family, distributed in tropical and subtropical regions with the center of biodiversity in Southeast Asia. The study about phytochemical contents Globba is an interesting especially Globba candida Gapnep which have been never reported. The aims of this study were to observe distribution and phytochemical compounds of ethanol extract of G. candida Gapnep. found on Bali Island. Hydrodistillation was used to determine the presence of its essential oil and a Gas Chromatography-Mass Spectrometry (GC-MS) was used to carry out the phytochemical analysis of the essential oil and ethanol extracts of G. candida Gapne. The phytochemical analysis of the rhizomes and leaves ethanol extracts of G. candida Gapnep revealed 36 and 8 identified chemical compounds representing 85,82% and 85,47% of the total analyzed extracts. However, there was no essential oil constituent found in G. candida Gapnep. The main compounds of the rhizome extract of G. candida Gapnep were levoglucosan 19.07%, allylhydrazone acetaldehyde 5.52%, trans-2,3-epoxybutane 6.30%, butan-3-enoic acid methyl ester 4.36%, 2-methylcyclopentanone 4.02%, and 2-n-propyl-oxetan 4.00%. While the dominant contents of the leaves extract of G. candida Gapnep were pinostrobin chalcone 75.63%.

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Section: Introductionmentioning

confidence: 99%

Distribution and Phytocomponent in the Ethanol Extract of Globba candida Gagnep. (Zingiberaceae) by GC-MS Analysis

Andila

Tirta²

2019

JTLS

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“…Genetically, modified flax might be the active source of antibacterial compounds and substitution to antibiotic therapy [18]. Turmeric Curcuma longa L. is a genus of 1200 species of rhizomatous herbs belongs to the family Zingiberaceae, which is an aromatic plant and has multiple uses and particularly in medicine, especially in India as a volatile oil [19]. The tuber roots of a few species of the genus Curcuma are economic sources of phytochemicals, pharmaceutical and perfumery compounds, which have antimicrobial and antioxidant compounds and exclude harmful organisms [20].…”

Section: Introductionmentioning

confidence: 99%

Antibacterial Effect of Fixed and Volatile Oils against Gram-positive and Gram-negative Bacteria

Salih

Abdullah

Ali

et al. 2019

KJAR

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Antibiotic resistance phenomena among pathogenic bacteria considered as a major health problem and associated with increased mortality or long-term hospitalization, which lead to open a new era by using plant and herbal extracts as an alternative source of various chemotherapeutic drugs, also to increase antibiotic efficiency by combining with plant extract for obtaining a powerful and broad spectrum action. The current investigation aims to investigate antibacterial actions of fixed oils of (Olea europaea L., Ricinus communis L. and Linum usitatissimum) and volatile oil of (Nigella sativa, Curcuma longa L and Zingiber officinale) against both Staphylococcus aureus strain (6734151) and Escherichia coli strain (5344572). This study conducted on antibacterial effect of six different extracted oils from medical herbs. The findings revealed that the oil extracts have different antibacterial activities with efficacy. Bacterial inhibition zone was detected by using disk diffusion method. Furthermore , volatile oil of N. sativa showed a great inhibitory action against resistant S. aureus, which was (27.7± 1.2 mm). The antimicrobial effects of other fixed and volatile oils against S. aureu, the inhibition zone was (10 ± 1.0 mm) for (Zingiber officinale), (9 ± 1.0 mm) for Ricinus communis L., (7.7 ± 0.6 mm) for Olea europea L., (7.3 ± 0.6 mm) for Linum usitatissimum and for Curcuma longa L. was (6.7 ± 0.6mm). Moreover, antimicrobial effect of N. sativa against E. coli was more active in comparison with other oils, while other oils showed a slight antibacterial effect. In conclusion, volatile oil of N. sativa reveals great antibacterial activities in comparison with other extracted oils.

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“…The spices belong to a group of plant products which are globally consumed because of their accessibility and low price. Besides favoring food, many spices have a long history of use in traditional medicine due to their useful pharmaceutical properties such as anticancer, antimicrobial, antioxidant, and anti‐inflammatory activities (Chen et al, ; Kumar, Asish, Sabu, & Balachandran, ; Stanić, ).…”

Section: Introductionmentioning

confidence: 99%

Cytotoxic effects of Etlingera pavieana rhizome on various cancer cells and identification of a potential anti-tumor component

et al. 2018

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Much effort over the last several decades has been made to identify new anticancer agents, preferably with reduced adverse side effects. In this study, cytotoxic activity of rhizome extract from Etlingera pavieana (Pierre ex Gagnep.) R.M.Sm. was assessed. We demonstrate that ethanolic extract (EE) of E. pavieana rhizome shows reduced viabilities of several cancer cell lines in doseand time-dependent manners. Following cytotoxic-guided isolation of EE, the bioactive compound trans-4-methoxycinnamaldehyde (4-MCA) was identified. 4-MCA exhibited a dose-dependent inhibitory effect on cancer cell growth with the IC 50 values ranging from 34 to 40 mM, which are approximately four times lower than that of noncancerous cells. This antiproliferative effect might be due to its cooperative actions of inducing apoptosis and arresting cell cycle at G2/M phase. To the best of our knowledge, this is the first report on the in vitro antitumor promoting activity of 4-MCA. Practical applications Rhizome of E. pavieana (Zingiberaceae) has been widely used as spices and a medicinal plant in Thailand, Cambodia, Laos, and Vietnam. In this study, we demonstrated the medicinal role of this plant on suppressing the growth of various cancer cells of common cancer types including those of breast, cervix, liver, and colon/rectum. Moreover, we verified that this action was, at least in part, due to one of its constituents, 4-MCA. Overall results demonstrated the potential cytotoxic activities of 4-MCA toward cancer cells, including inhibition of cell proliferation and colony formation, induction of apoptosis, and cell cycle arrest whereas it exhibited negligible effect on noncancerous cells. The comprehensive characterization of E. pavieana rhizome performed in this study, highlights the pharmaceutical potential of 4-MCA, one of its major constituents, to be a promising candidate for future development of new cancer regimen. K E Y W O R D S apoptosis induction, cell cycle arrest, cytotoxicity, Etlingera pavieana, 4-methoxycinnamaldehyde

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Significance of gingers (Zingiberaceae) in Indian System of Medicine - Ayurveda: An overview

Cited by 65 publications

References 23 publications

Distribution and Phytocomponent in the Ethanol Extract of Globba candida Gagnep. (Zingiberaceae) by GC-MS Analysis

Distribution and Phytocomponent in the Ethanol Extract of Globba candida Gagnep. (Zingiberaceae) by GC-MS Analysis

Antibacterial Effect of Fixed and Volatile Oils against Gram-positive and Gram-negative Bacteria

Cytotoxic effects of Etlingera pavieana rhizome on various cancer cells and identification of a potential anti-tumor component

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