Significance of lymph node metastasis in patients with diffuse malignant peritoneal mesothelioma

Yan, Tristan D.; Yoo, Dal; Sugarbaker, Paul H.

doi:10.1016/j.ejso.2006.05.009

Cited by 67 publications

(53 citation statements)

References 26 publications

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“…Sixty-five percent of patients treated in our unit had a complete cytoreduction. Although it has been reported in the literature that PCI is prognostic for survival [10,11], we did not detect any relationship of PCI on survival (P ¼ 0.681) in our cohort. We acknowledge that the small sample size may not detect such a difference.…”

Section: Discussioncontrasting

confidence: 85%

Outcomes of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal mesothelioma: The Australian experience

Chua

Yan

Morris

2008

Journal of Surgical Oncology

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Section: Discussioncontrasting

confidence: 85%

Outcomes of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal mesothelioma: The Australian experience

Chua

Yan

Morris

2008

Journal of Surgical Oncology

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“…Yan et al [2009] showed that patients with positive lymph nodes had a median survival of 20 vs. 56 months for patients without positive nodes (54). This data strengthens the finding by that same group in 2006 which showed survival of 6 months in lymph nodepositive patients vs. 59 months in lymph node-negative patients (85). This finding was also found in 2013 by Baratti and associates (58).…”

Section: Prognosissupporting

confidence: 79%

Malignant peritoneal mesothelioma: a review

2017

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Mesothelioma is a malignancy of serosal membranes. It is most commonly encountered in the visceral pleura with the second most common location in the peritoneum. The diagnosis is very rare and has been linked to toxic exposure to industrial pollutants, especially asbestos. Malignant peritoneal mesothelioma (MPM) commonly presents with diffuse, extensive spread throughout the abdomen with rare metastatic spread beyond the abdominal cavity. Due to its rarity and nonspecific symptoms, it is usually diagnosed late when the disease burden is extensive. Because pleural mesothelioma is more common than MPM, most research has been on the pleural variant and extrapolated for MPM. While treatment advances have been made for MPM, the disease is universally fatal from either abdominal complications secondary to the spread of disease or starvation.Untreated, the life expectancy is less than a year. Cytoreductive surgery (CRS) with heated intraperitoneal chemotherapy (HIPEC) has become the mainstay of therapy with systemic therapies still being developed. We will review the epidemiology of MPM and discuss diagnostic and treatment strategies.

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“…Data from the Washington Cancer Institute showed that 7 patients had positive lymph nodes. 18 Their median survival was 6 months, with 1-and 2-year survival of 43% and 0%, respectively. Ninety-three patients had absence of lymph node involvement and their median survival was 59 months, with 5-and 7-year survival of 50% and 43%, respectively.…”

Section: Proposed Tnm Staging Systemmentioning

confidence: 97%

“…Ninety-three patients had absence of lymph node involvement and their median survival was 59 months, with 5-and 7-year survival of 50% and 43%, respectively. 18 Baratti and coworkers demonstrated a 5-year survival of 82.5% for patients with pathologically negative lymph nodes, compared with 16.7% for those with positive lymph nodes. 19 Inclusion of a N stage in a TNM system for DMPM may lead to improved intraoperative assessment of the prognosis.…”

Section: Proposed Tnm Staging Systemmentioning

confidence: 98%

See 1 more Smart Citation

A novel tumor‐node‐metastasis (TNM) staging system of diffuse malignant peritoneal mesothelioma using outcome analysis of a multi‐institutional database*

Yan

Deraco²,

Élias

et al. 2010

Cancer

135

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A novel digital active homodyne demodulation scheme to eliminate the signal fading in interferometric fiber‐optic sensors is proposed. The error signal is obtained by the square‐wave phase modulation and then the digital correlation detection technique is applied to demodulate the low‐frequency environmental phase drift and generate the offset phase, which is then fed back the integrated optical phase modulator to lock the interferometer in quadrature. The high‐frequency signal phase can be read out and recovered from the photodetector output with the interferometer in quadrature. The simulation and experimental results verify the feasibility of the proposed scheme, which obviates the feedback integrator saturation and the system resetting problem encountered in the conventional active homodyne detection schemes. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:20–23, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.25640

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Significance of lymph node metastasis in patients with diffuse malignant peritoneal mesothelioma

Cited by 67 publications

References 26 publications

Outcomes of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal mesothelioma: The Australian experience

Outcomes of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal mesothelioma: The Australian experience

Malignant peritoneal mesothelioma: a review

A novel tumor‐node‐metastasis (TNM) staging system of diffuse malignant peritoneal mesothelioma using outcome analysis of a multi‐institutional database*

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