Significance of preoperative use of ultrasonography in parathyroid neoplasms: Comparison of sonographic textures with histologic findings

Abstract

The sonographic textures of 10 parathyroid tumors in nine patients were examined and compared with their histologic features, particularly with the amount of fibrous trabeculae. The carcinomas containing a large amount of fibrous trabeculae, which is the most frequent finding in parathyroid cancer, were very echogenic. On the other hand, the adenomas without fibrous trabeculae showed a low echogenicity. These data suggest that the possibility of malignancy is high when the parathyroid tumor is found to be very echogenic.

Ultrasonographic Features of Parathyroid Carcinoma.

“…In addition, Kinoshita et al reported that a parathyroid tumor with high echogenicity is more likely to be a carcinoma than an adenoma [16]. However, Edmonson et al and Daly et al did not support this conclusion [17,18], and our findings are consistent with those reported by these authors.…”

“…Interestingly, two of the three adenomas with a DW ratio >_ 1 were associated with either chronic thyroiditis or thyroid tumor, and the third adenoma did not lie beneath the thyroid gland. DW ratio = D (depth)/W (width) accounting for fewer than 1 % of cases of primary hyperparathyroidism, literature regarding its ultrasonographic features is limited [16][17][18][19]25]. Moreover, previous reports included relatively few cases of parathyroid carcinoma.…”

“…Because ultrasonography of the neck has been used for preoperative localization studies in patients with HPT, several investigators have described the sonographic features of parathyroid carcinoma in illustrative cases [16][17][18][19]. As has been demonstrated for thyroid and breast cancers [20][21][22][23][24], the shape, borders, internal echogenicity, and depth-width (DW) ratio of parathyroid tumors likely are indicators of malignancy.…”

Ultrasound features of malignancy in the preoperative diagnosis of parathyroid cancer: a retrospective analysis of parathyroid tumours larger than 15 mm

“…isiknowledge.com/). This identified a total of 2 further studies, giving a total of 15 studies [15,16,[18][19][20][21][22][23][24][25][26][27][28][29][30].…”

Sonographische Diagnostik eines Nebenschilddrüsenkarzinoms

“…Beim Überwiegen fibröser Tumoranteile, evtl. auch in Abhängig-keit von der Schallfrequenz (3,5 MHz Real-time-linear Scanner), wurden auch gleichmäßig echoreich erscheinende Echomuster, ähnlich des angrenzenden Schilddrüsenparenchyms, beschrieben[25]. Beim Einsatz hochfrequenter Real-time-Sonographie-Geräte (7,5 -10 MHz) lag der durchschnittliche Durchmesser der Nebenschilddrüsenkarzinome bei 2,4 cm bei rundlicher oder ovoider Form und lobulierter Randkontur.…”