Significance of serum miR‐29a in the occurrence and progression of diabetic nephropathy: A cross‐sectional study

Abstract

Type 2 diabetes mellitus (T2DM) is a common metabolic disease that threatens human health, and as it progresses, it often causes a series of microvascular complications. [1][2][3] Diabetic nephropathy (DN), one of the most common microvascular complications of T2DM, is an important factor causing chronic kidney disease and has been reported to occur in approximately 40% of T2DM patients. 4 Although the

MicroRNA‐29‐mediated cross‐talk between metabolic organs in the pathogenesis of diabetes mellitus and its complications: A narrative review

“…MicroRNA-29 has been implicated in the pathogenesis of diabetic nephropathy, which is a common complication of diabetes characterized by kidney damage and progressive decline in renal function. 96 MicroRNA-29 plays a multifaceted role in the pathogenesis of diabetic nephropathy by affecting fibrosis, epithelial-to-mesenchymal transition (EMT), inflammation, and glucose metabolism. 97 Chien and his colleagues have made a significant discovery regarding the potential role of a cascade involving microRNA-29a/b/c in the development of diabetic nephropathy (DN).…”

“…MicroRNA‐29 has been implicated in the pathogenesis of diabetic nephropathy, which is a common complication of diabetes characterized by kidney damage and progressive decline in renal function 96 . MicroRNA‐29 plays a multifaceted role in the pathogenesis of diabetic nephropathy by affecting fibrosis, epithelial‐to‐mesenchymal transition (EMT), inflammation, and glucose metabolism 97 .…”